Osteogenic Protein-1: Gene Expression and Treatment in the Rat Remnant Kidney Model

Osteogenic Protein-1 (OP-1) is a bone morphogen involved in tissue repair and development. We have shown that OP-1 is downregulated during acute ischemic renal injury. Here we report the use of the rat remnant kidney model (RRKM) to evaluate changes in kidney OP-1 expression during chronic injury, a...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Toxicologic pathology 2004-07, Vol.32 (4), p.384-392
Hauptverfasser:	Dube, Philip H., Almanzar, Maria M., Frazier, Kendall S., Jones, William K., Charette, Marc F., Paredes, Ana
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bone Morphogenetic Protein 7 Bone Morphogenetic Proteins - genetics Bone Morphogenetic Proteins - metabolism Disease Models, Animal Dose-Response Relationship, Drug Down-Regulation Female Gene Expression Humans Kidney - drug effects Kidney - injuries Kidney - metabolism Kidney Failure, Chronic - etiology Kidney Failure, Chronic - pathology Nephrectomy Rats Rats, Sprague-Dawley Recombinant Proteins - therapeutic use RNA, Messenger - metabolism Time Factors Transforming Growth Factor beta - genetics Transforming Growth Factor beta - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!