Influence of endotracheal tube bore on tidal volume during high frequency oscillatory ventilation: a model lung study
In adults, the influence of endotracheal tube bore on tidal volume (VT) during high-frequency oscillatory ventilation (HFOV) has been little studied. Via full-length 6, 7, 8, and 9 mm internal diameter (ID) endotracheal tubes (ETTs), a model lung (TTL, Michigan Instruments, MI) was ventilated using...
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| Veröffentlicht in: | Medical science monitor 2009-01, Vol.15 (1), p.MT1-MT4 |
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| creator | Hirao, Osamu Iguchi, Naoya Uchiyama, Akinori Mashimo, Takashi Nishimura, Masaji Fujino, Yuji |
| description | In adults, the influence of endotracheal tube bore on tidal volume (VT) during high-frequency oscillatory ventilation (HFOV) has been little studied.
Via full-length 6, 7, 8, and 9 mm internal diameter (ID) endotracheal tubes (ETTs), a model lung (TTL, Michigan Instruments, MI) was ventilated using a high-frequency oscillator designed for adult patients (R100; Metran, Japan). Oscillation settings were: frequency, 5, 7, and 9 Hz; mean airway pressure, 15 cmH2O; oxygen inspiratory fraction, 0.21. At each setting: oscillator pressure swing was set at maximum; and each test combination was conducted with the model-lung compliance set at 20 and 50 mL/cmH2O. During the trials, a position sensor attached to the model-lung upper surface provided analog electrical signals for lung movement that were converted to VT evaluation data. Pressure and volume signals were digitized using an analog-to-digital converter and recorded in a computer. At each setting, three waveforms were analyzed and the average value used.
At each setting, measured VT was proportional to ETT internal cross-sectional area (CSA). Regression analysis of VT showed correlation with the CSA, as expressed by formula, y=2.173x where x is CSA and y is VT (R2=0.99, p |
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Via full-length 6, 7, 8, and 9 mm internal diameter (ID) endotracheal tubes (ETTs), a model lung (TTL, Michigan Instruments, MI) was ventilated using a high-frequency oscillator designed for adult patients (R100; Metran, Japan). Oscillation settings were: frequency, 5, 7, and 9 Hz; mean airway pressure, 15 cmH2O; oxygen inspiratory fraction, 0.21. At each setting: oscillator pressure swing was set at maximum; and each test combination was conducted with the model-lung compliance set at 20 and 50 mL/cmH2O. During the trials, a position sensor attached to the model-lung upper surface provided analog electrical signals for lung movement that were converted to VT evaluation data. Pressure and volume signals were digitized using an analog-to-digital converter and recorded in a computer. At each setting, three waveforms were analyzed and the average value used.
At each setting, measured VT was proportional to ETT internal cross-sectional area (CSA). Regression analysis of VT showed correlation with the CSA, as expressed by formula, y=2.173x where x is CSA and y is VT (R2=0.99, p<0.001) at 5 Hz and compliance of 50 cmH2O.
In an adult-simulating model lung, VT during HFOV varies in proportion to ETT CSA.</description><identifier>EISSN: 1643-3750</identifier><identifier>PMID: 19114975</identifier><language>eng</language><publisher>United States</publisher><subject>Adult ; High-Frequency Ventilation - instrumentation ; High-Frequency Ventilation - methods ; Humans ; Intubation, Intratracheal - instrumentation ; Lung - physiology ; Models, Anatomic ; Regression Analysis ; Tidal Volume - physiology</subject><ispartof>Medical science monitor, 2009-01, Vol.15 (1), p.MT1-MT4</ispartof><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19114975$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hirao, Osamu</creatorcontrib><creatorcontrib>Iguchi, Naoya</creatorcontrib><creatorcontrib>Uchiyama, Akinori</creatorcontrib><creatorcontrib>Mashimo, Takashi</creatorcontrib><creatorcontrib>Nishimura, Masaji</creatorcontrib><creatorcontrib>Fujino, Yuji</creatorcontrib><title>Influence of endotracheal tube bore on tidal volume during high frequency oscillatory ventilation: a model lung study</title><title>Medical science monitor</title><addtitle>Med Sci Monit</addtitle><description>In adults, the influence of endotracheal tube bore on tidal volume (VT) during high-frequency oscillatory ventilation (HFOV) has been little studied.
Via full-length 6, 7, 8, and 9 mm internal diameter (ID) endotracheal tubes (ETTs), a model lung (TTL, Michigan Instruments, MI) was ventilated using a high-frequency oscillator designed for adult patients (R100; Metran, Japan). Oscillation settings were: frequency, 5, 7, and 9 Hz; mean airway pressure, 15 cmH2O; oxygen inspiratory fraction, 0.21. At each setting: oscillator pressure swing was set at maximum; and each test combination was conducted with the model-lung compliance set at 20 and 50 mL/cmH2O. During the trials, a position sensor attached to the model-lung upper surface provided analog electrical signals for lung movement that were converted to VT evaluation data. Pressure and volume signals were digitized using an analog-to-digital converter and recorded in a computer. At each setting, three waveforms were analyzed and the average value used.
At each setting, measured VT was proportional to ETT internal cross-sectional area (CSA). Regression analysis of VT showed correlation with the CSA, as expressed by formula, y=2.173x where x is CSA and y is VT (R2=0.99, p<0.001) at 5 Hz and compliance of 50 cmH2O.
In an adult-simulating model lung, VT during HFOV varies in proportion to ETT CSA.</description><subject>Adult</subject><subject>High-Frequency Ventilation - instrumentation</subject><subject>High-Frequency Ventilation - methods</subject><subject>Humans</subject><subject>Intubation, Intratracheal - instrumentation</subject><subject>Lung - physiology</subject><subject>Models, Anatomic</subject><subject>Regression Analysis</subject><subject>Tidal Volume - physiology</subject><issn>1643-3750</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo1kM1LxDAQxYsg7rr6L0hO3gqTtE1bb7L4sbDgRc8lTSa7kTRZ87HQ_96KeprHvN8bHnNRrCmvq7JqG1gV1zF-ArCOQ3NVrGhPad23zbrIO6dtRieReE3QKZ-CkEcUlqQ8Ihl9WBxHklHL6uxtnpCoHIw7kKM5HIkO-PWTn4mP0lgrkg8zOaNLZtHGuwciyOQVWmLzEoopq_mmuNTCRrz9m5vi4_npffta7t9edtvHfXli0KeS9kxXIxdd3QNnoChruFDQyEowDiDakddQgZKoa800rVsqOKu17DoA1LLaFPe_d0_BLy1jGiYTJS4tHfocB87bDrqGLuDdH5jHCdVwCmYSYR7-H1V9A_ntZWM</recordid><startdate>200901</startdate><enddate>200901</enddate><creator>Hirao, Osamu</creator><creator>Iguchi, Naoya</creator><creator>Uchiyama, Akinori</creator><creator>Mashimo, Takashi</creator><creator>Nishimura, Masaji</creator><creator>Fujino, Yuji</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>200901</creationdate><title>Influence of endotracheal tube bore on tidal volume during high frequency oscillatory ventilation: a model lung study</title><author>Hirao, Osamu ; Iguchi, Naoya ; Uchiyama, Akinori ; Mashimo, Takashi ; Nishimura, Masaji ; Fujino, Yuji</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p209t-192f3b6a8490620d1256ad05c3a2600a7b64030dcef4f2f1471a624fc8800efc3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>Adult</topic><topic>High-Frequency Ventilation - instrumentation</topic><topic>High-Frequency Ventilation - methods</topic><topic>Humans</topic><topic>Intubation, Intratracheal - instrumentation</topic><topic>Lung - physiology</topic><topic>Models, Anatomic</topic><topic>Regression Analysis</topic><topic>Tidal Volume - physiology</topic><toplevel>online_resources</toplevel><creatorcontrib>Hirao, Osamu</creatorcontrib><creatorcontrib>Iguchi, Naoya</creatorcontrib><creatorcontrib>Uchiyama, Akinori</creatorcontrib><creatorcontrib>Mashimo, Takashi</creatorcontrib><creatorcontrib>Nishimura, Masaji</creatorcontrib><creatorcontrib>Fujino, Yuji</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Medical science monitor</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hirao, Osamu</au><au>Iguchi, Naoya</au><au>Uchiyama, Akinori</au><au>Mashimo, Takashi</au><au>Nishimura, Masaji</au><au>Fujino, Yuji</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Influence of endotracheal tube bore on tidal volume during high frequency oscillatory ventilation: a model lung study</atitle><jtitle>Medical science monitor</jtitle><addtitle>Med Sci Monit</addtitle><date>2009-01</date><risdate>2009</risdate><volume>15</volume><issue>1</issue><spage>MT1</spage><epage>MT4</epage><pages>MT1-MT4</pages><eissn>1643-3750</eissn><abstract>In adults, the influence of endotracheal tube bore on tidal volume (VT) during high-frequency oscillatory ventilation (HFOV) has been little studied.
Via full-length 6, 7, 8, and 9 mm internal diameter (ID) endotracheal tubes (ETTs), a model lung (TTL, Michigan Instruments, MI) was ventilated using a high-frequency oscillator designed for adult patients (R100; Metran, Japan). Oscillation settings were: frequency, 5, 7, and 9 Hz; mean airway pressure, 15 cmH2O; oxygen inspiratory fraction, 0.21. At each setting: oscillator pressure swing was set at maximum; and each test combination was conducted with the model-lung compliance set at 20 and 50 mL/cmH2O. During the trials, a position sensor attached to the model-lung upper surface provided analog electrical signals for lung movement that were converted to VT evaluation data. Pressure and volume signals were digitized using an analog-to-digital converter and recorded in a computer. At each setting, three waveforms were analyzed and the average value used.
At each setting, measured VT was proportional to ETT internal cross-sectional area (CSA). Regression analysis of VT showed correlation with the CSA, as expressed by formula, y=2.173x where x is CSA and y is VT (R2=0.99, p<0.001) at 5 Hz and compliance of 50 cmH2O.
In an adult-simulating model lung, VT during HFOV varies in proportion to ETT CSA.</abstract><cop>United States</cop><pmid>19114975</pmid></addata></record> |
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| ispartof | Medical science monitor, 2009-01, Vol.15 (1), p.MT1-MT4 |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Adult High-Frequency Ventilation - instrumentation High-Frequency Ventilation - methods Humans Intubation, Intratracheal - instrumentation Lung - physiology Models, Anatomic Regression Analysis Tidal Volume - physiology |
| title | Influence of endotracheal tube bore on tidal volume during high frequency oscillatory ventilation: a model lung study |
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