β-d-Glucan as a Diagnostic Adjunct for Invasive Fungal Infections: Validation, Cutoff Development, and Performance in Patients with Acute Myelogenous Leukemia and Myelodysplastic Syndrome

The Glucatell (1→3)-β-d-glucan (BG) detection assay (Associates of Cape Cod) was studied as a diagnostic adjunct for invasive fungal infections (IFIs). On the basis of findings from a preliminary study of 30 candidemic subjects and 30 healthy adults, a serum BG level of ⩾60 pg/mL was chosen as the c...

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Veröffentlicht in:	Clinical infectious diseases 2004-07, Vol.39 (2), p.199-205
Hauptverfasser:	Odabasi, Zekaver, Mattiuzzi, Gloria, Estey, Elihu, Kantarjian, Hagop, Saeki, Fumihiro, Ridge, Richard J., Ketchum, Paul A., Finkelman, Malcolm A., Rex, John H., Ostrosky-Zeichner, Luis
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antibiotics. Antiinfectious agents. Antiparasitic agents Antifungal agents Antifungals Aspergillosis beta-Glucans - blood Biological and medical sciences Blood Candidemia Candidiasis - blood Fungal infections Fungemia - blood Glucans Hematologic and hematopoietic diseases Human mycoses Humans Infectious diseases Kinetics Leukemia, Myeloid, Acute - blood Leukemia, Myeloid, Acute - complications Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Limulus Test Major Articles Medical sciences Miscellaneous mycoses Mycoses Mycoses - blood Mycoses - complications Mycoses - diagnosis Myelodysplastic Syndromes - blood Myelodysplastic Syndromes - complications Myeloid leukemia Neutropenia - blood Neutropenia - complications Pharmacology. Drug treatments Polysaccharides - blood Predictive Value of Tests Reagent Kits, Diagnostic Reagents Sensitivity and Specificity Specimens
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