Intestinal ischemia as the first manifestation of vasculitis

To summarize current knowledge regarding the diagnosis and management of gastrointestinal vasculitis. Three cases of gastrointestinal vasculitis with acute abdominal ischemia as their first manifestation are presented. Underlying diseases were microscopic polyangiitis, systemic lupus erythematosus (...

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Veröffentlicht in:Seminars in arthritis and rheumatism 2004-08, Vol.34 (1), p.431-441
Hauptverfasser: Passam, Freda H., Diamantis, Ioannis D., Perisinaki, Garyfalia, Saridaki, Zenia, Kritikos, Herakles, Georgopoulos, Dimitrios, Boumpas, Dimitrios T.
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container_end_page 441
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container_title Seminars in arthritis and rheumatism
container_volume 34
creator Passam, Freda H.
Diamantis, Ioannis D.
Perisinaki, Garyfalia
Saridaki, Zenia
Kritikos, Herakles
Georgopoulos, Dimitrios
Boumpas, Dimitrios T.
description To summarize current knowledge regarding the diagnosis and management of gastrointestinal vasculitis. Three cases of gastrointestinal vasculitis with acute abdominal ischemia as their first manifestation are presented. Underlying diseases were microscopic polyangiitis, systemic lupus erythematosus (SLE), and polyarteritis nodosa (PAN). Relevant English-language articles collected from the PubMed database were reviewed. Among the angiitides, PAN, SLE, and Henoch-Schönlein are those most commonly accompanied by gastrointestinal complications. Intestinal vasculitis usually occurs when there is evidence of generalized disease activity. Abdominal computerized tomography is a valuable tool for diagnosing intestinal ischemia and suspected vasculitis. In young patients presenting with intestinal ischemia, it is essential to assess the possibility of an underlying systemic disease. With prompt initiation of immunosuppressive treatment, surgery may be avoided. Prognosis is improved when there is minimal delay in surgical intervention.
doi_str_mv 10.1016/j.semarthrit.2003.12.004
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subjects Abdomen, Acute - diagnosis
Abdomen, Acute - etiology
abdominal pain
Abdominal Pain - diagnosis
Abdominal Pain - etiology
Adult
Biological and medical sciences
Diagnosis, Differential
Diseases of the osteoarticular system
Fatal Outcome
Female
Follow-Up Studies
gastrointestinal ischemia
Humans
Intestines - blood supply
Ischemia - diagnosis
Laparotomy
Lupus Erythematosus, Systemic - diagnosis
Male
Medical sciences
Middle Aged
Polyarteritis Nodosa - diagnosis
Risk Assessment
Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis
Vasculitis
Vasculitis - diagnosis
title Intestinal ischemia as the first manifestation of vasculitis
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