Neurotrophic effects of talaumidin, a neolignan from Aristolochia arcuata, in primary cultured rat cortical neurons

Abstract Talaumidin, a tetrahydrofuran neolignan isolated from the root of ARISTOLOCHIA ARCUATA, was shown to be an intriguing small molecule with neurotrophic activity in the primary culture of rat cortical neurons. Talaumidin can promote both dendrite-like and axon-like process outgrowth of cultur...

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Veröffentlicht in:	Planta medica 2004-07, Vol.70 (7), p.598-602
Hauptverfasser:	Zhai, H, Nakatsukasa, M, Mitsumoto, Y, Fukuyama, Y
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Aristolochia Aristolochia arcuata Barbiturates Biological and medical sciences cell growth Cell Survival Cells, Cultured cerebral cortex Cerebral Cortex - cytology Cerebral Cortex - drug effects cultured cells dendrites Female Furans General pharmacology lignans Lignans - administration & dosage Lignans - pharmacology Medical sciences medicinal plants neolignan neurons Neurons - cytology Neurons - drug effects Neuroprotective Agents - administration & dosage Neuroprotective Agents - pharmacology neuroprotective effect Original Paper Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments phytochemicals Phytotherapy plant extracts Plant Extracts - administration & dosage Plant Extracts - pharmacology Pregnancy Rats Rats, Sprague-Dawley talaumidin
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