Detection of CFTR mutations using temporal temperature gradient gel electrophoresis

Cystic fibrosis (CF), caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, is one of the most common autosomal recessive diseases with variable incidences and mutation spectra among different ethnic groups. Current commercially available mutation panels designe...

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Veröffentlicht in:	Electrophoresis 2004-08, Vol.25 (15), p.2593-2601
Hauptverfasser:	Wong, Lee-Jun C., Alper, Özgül M.
Format:	Artikel
Sprache:	eng
Schlagworte:	CFTR mutation Cystic Fibrosis - genetics Cystic Fibrosis Transmembrane Conductance Regulator - genetics DNA Primers - genetics Electrophoresis, Agar Gel - methods Hispanic Americans Homozygote Humans Mutation - genetics Mutation detection Polymorphism, Genetic Temperature Temporal temperature gradient gel electrophoresis
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