Abnormal Angiogenesis in Foxo1 (Fkhr)-deficient Mice

Members of the Foxo family, Foxo1 ( Fkhr ), Foxo3 ( Fkhrl1 ), and Foxo4 (Afx), are mammalian homologs of daf-16 , which influences life span and energy metabolism in Caenorhabditis elegans . Mammalian FOXO proteins also play important roles in cell cycle arrest, apoptosis, stress resistance, and ene...

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Veröffentlicht in:	The Journal of biological chemistry 2004-08, Vol.279 (33), p.34741-34749
Hauptverfasser:	Furuyama, Tatsuo, Kitayama, Kazuko, Shimoda, Yuri, Ogawa, Minetaro, Sone, Kiyoaki, Yoshida-Araki, Kiyomi, Hisatsune, Hiroshi, Nishikawa, Shin-ichi, Nakayama, Keiko, Nakayama, Keiichi, Ikeda, Kyoji, Motoyama, Noboru, Mori, Nozomu
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigens, CD Cadherins - metabolism Cell Differentiation Embryo, Mammalian - metabolism Endothelial Cells - metabolism Endothelium, Vascular - metabolism Forkhead Box Protein O1 Forkhead Transcription Factors Genotype Immunohistochemistry In Situ Hybridization Mice Mice, Transgenic Models, Genetic Neovascularization, Pathologic Reverse Transcriptase Polymerase Chain Reaction Time Factors Transcription Factors - genetics Transcription Factors - physiology Vascular Endothelial Growth Factor A - metabolism
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