Comparative efficacy of Topical gatifloxacin with ciprofloxacin, amikacin, and clarithromycin in the Treatment of Experimental Mycobacterium chelonae keratitis

To determine the comparative efficacy of topical gatifloxacin with ciprofloxacin, fortified amikacin, and clarithromycin against Mycobacterium chelonae keratitis in an animal model. Experimental M chelonae keratitis was induced via intrastromal inoculation in a rabbit model. Thirty-five rabbits were...

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Veröffentlicht in:	Archives of ophthalmology (1960) 2004-08, Vol.122 (8), p.1166-1169
Hauptverfasser:	HYON, Joon-Young, JOO, Myung-Jin, HOSE, Stacey, SINHA, Debasish, DICK, James D, O'BRIEN, Terrence P
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Topical Amikacin - administration & dosage Amikacin - therapeutic use Animals Anti-Bacterial Agents - administration & dosage Anti-Bacterial Agents - therapeutic use Biological and medical sciences Ciprofloxacin - administration & dosage Ciprofloxacin - therapeutic use Clarithromycin - administration & dosage Clarithromycin - therapeutic use Cornea - microbiology Corneal Ulcer - drug therapy Corneal Ulcer - microbiology Disease Models, Animal Diseases of cornea, anterior segment and sclera Drug Therapy, Combination Eye Infections, Bacterial - drug therapy Eye Infections, Bacterial - microbiology Fluoroquinolones - administration & dosage Fluoroquinolones - therapeutic use Male Medical sciences Mycobacterium Mycobacterium chelonae Mycobacterium chelonae - isolation & purification Mycobacterium Infections, Nontuberculous - drug therapy Mycobacterium Infections, Nontuberculous - microbiology Ophthalmic Solutions - administration & dosage Ophthalmic Solutions - therapeutic use Ophthalmology Rabbits
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