Primary biliary cirrhosis in monozygotic and dizygotic twins: genetics, epigenetics, and environment

There is growing evidence that the interplay of genetic susceptibility and environmental factors leads to primary biliary cirrhosis (PBC). In particular, family members of an infected individual have up to a 100-fold higher risk of developing PBC. Although concordant rates for identical twins in oth...

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Veröffentlicht in:	Gastroenterology (New York, N.Y. 1943) N.Y. 1943), 2004-08, Vol.127 (2), p.485-492
Hauptverfasser:	Selmi, Carlo, Mayo, Marlyn J, Bach, Nancy, Ishibashi, Hiromi, Invernizzi, Pietro, Gish, Robert G, Gordon, Stuart C, Wright, Harlan I, Zweiban, Bruce, Podda, Mauro, Gershwin, M Eric
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Environment Epigenesis, Genetic Female Humans Liver Cirrhosis, Biliary - diagnosis Liver Cirrhosis, Biliary - genetics Male Middle Aged Polymorphism, Genetic Tandem Repeat Sequences Twins, Dizygotic Twins, Monozygotic
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