Refined Porcine Follicle Stimulating Hormone Promotes the Responsiveness of Rabbits to Multiple-Ovulation Treatment
We investigated whether refined follicle stimulating hormone (FSH) with only a little contaminating LH can promote the responsiveness of rabbits to multiple-ovulation treatment. One group of female rabbits was stimulated with refined porcine FSH (pFSH), an FSH source with low LH activity, and anothe...
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Veröffentlicht in: | Experimental Animals 2004, Vol.53(4), pp.395-397 |
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creator | HASHIMOTO, Shu KURAMOCHI, Takashi AOYAGI, Kazuki TAKAHASHI, Ri-ichi UEDA, Masatsugu HIRAO, Masao KAMEI, Mikako KITADA, Kensaku HIRASAWA, Kazuo |
description | We investigated whether refined follicle stimulating hormone (FSH) with only a little contaminating LH can promote the responsiveness of rabbits to multiple-ovulation treatment. One group of female rabbits was stimulated with refined porcine FSH (pFSH), an FSH source with low LH activity, and another group was treated with pFSH. The mean number of eggs recovered from donors stimulated with refined pFSH (27 ± 3) was significantly greater (P |
doi_str_mv | 10.1538/expanim.53.395 |
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One group of female rabbits was stimulated with refined porcine FSH (pFSH), an FSH source with low LH activity, and another group was treated with pFSH. The mean number of eggs recovered from donors stimulated with refined pFSH (27 ± 3) was significantly greater (P<0.05) than that with pFSH (20 ± 2). Furthermore, the mean number of remaining follicles of donors stimulated with refined pFSH (19 ± 4) was significantly greater (P<0.05) than that with pFSH (12 ± 1). To decrease the number of remaining follicles in donors treated with refined pFSH, the dose of human chorionic gonadotropin (hCG) was increased from 75 to 150. However, there were no differences in the numbers of eggs and remaining follicles. The results of the present study suggest that refined pFSH with little contaminating LH promotes the responsiveness of rabbits to multiple-ovulation treatment compared with pFSH.</description><identifier>ISSN: 1341-1357</identifier><identifier>EISSN: 1881-7122</identifier><identifier>DOI: 10.1538/expanim.53.395</identifier><identifier>PMID: 15297716</identifier><language>eng</language><publisher>Japan: Japanese Association for Laboratory Animal Science</publisher><subject>Animals ; Female ; Follicle Stimulating Hormone - isolation & purification ; Follicle Stimulating Hormone - pharmacology ; follicle-stimulating hormone ; multiple-ovulation ; Ovulation - drug effects ; Pregnancy ; Rabbits ; Superovulation - physiology</subject><ispartof>Experimental Animals, 2004, Vol.53(4), pp.395-397</ispartof><rights>2004 Japanese Association for Laboratory Animal Science</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c563t-b937be3596974d541d05c5f220e261b82dd799c43811d1c0d3bb22dc1b5ba6593</citedby><cites>FETCH-LOGICAL-c563t-b937be3596974d541d05c5f220e261b82dd799c43811d1c0d3bb22dc1b5ba6593</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,1881,27923,27924</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15297716$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>HASHIMOTO, Shu</creatorcontrib><creatorcontrib>KURAMOCHI, Takashi</creatorcontrib><creatorcontrib>AOYAGI, Kazuki</creatorcontrib><creatorcontrib>TAKAHASHI, Ri-ichi</creatorcontrib><creatorcontrib>UEDA, Masatsugu</creatorcontrib><creatorcontrib>HIRAO, Masao</creatorcontrib><creatorcontrib>KAMEI, Mikako</creatorcontrib><creatorcontrib>KITADA, Kensaku</creatorcontrib><creatorcontrib>HIRASAWA, Kazuo</creatorcontrib><title>Refined Porcine Follicle Stimulating Hormone Promotes the Responsiveness of Rabbits to Multiple-Ovulation Treatment</title><title>Experimental Animals</title><addtitle>Exp Anim</addtitle><description>We investigated whether refined follicle stimulating hormone (FSH) with only a little contaminating LH can promote the responsiveness of rabbits to multiple-ovulation treatment. One group of female rabbits was stimulated with refined porcine FSH (pFSH), an FSH source with low LH activity, and another group was treated with pFSH. The mean number of eggs recovered from donors stimulated with refined pFSH (27 ± 3) was significantly greater (P<0.05) than that with pFSH (20 ± 2). Furthermore, the mean number of remaining follicles of donors stimulated with refined pFSH (19 ± 4) was significantly greater (P<0.05) than that with pFSH (12 ± 1). To decrease the number of remaining follicles in donors treated with refined pFSH, the dose of human chorionic gonadotropin (hCG) was increased from 75 to 150. However, there were no differences in the numbers of eggs and remaining follicles. The results of the present study suggest that refined pFSH with little contaminating LH promotes the responsiveness of rabbits to multiple-ovulation treatment compared with pFSH.</description><subject>Animals</subject><subject>Female</subject><subject>Follicle Stimulating Hormone - isolation & purification</subject><subject>Follicle Stimulating Hormone - pharmacology</subject><subject>follicle-stimulating hormone</subject><subject>multiple-ovulation</subject><subject>Ovulation - drug effects</subject><subject>Pregnancy</subject><subject>Rabbits</subject><subject>Superovulation - physiology</subject><issn>1341-1357</issn><issn>1881-7122</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpNkE1P3DAQhi3UCijttcfKp96yje04To7VqpRKVKAFzpY_JmDk2KntIPrva7or2svMSO8z7-FB6CNpN4Sz4Qs8Lyq4ecPZho38CJ2SYSCNIJS-qTfrSEMYFyfoXc6PbUuFoOMxOiGcjkKQ_hTlHUwugMXXMZl64PPovTMe8E1x8-pVceEeX8Q0xxpepzjHAhmXB8A7yEsM2T1BgJxxnPBOae1KTSP-ufriFg_N1dPfkhjwbQJVZgjlPXo7KZ_hw2Gfobvzb7fbi-by6vuP7dfLxvCelUaPTGhgfOxH0VneEdtywydKW6A90QO1Voyj6dhAiCWmtUxrSq0hmmvV85Gdoc_73iXFXyvkImeXDXivAsQ1y76vDgbKK7jZgybFnBNMckluVum3JK180SwPmiVnsmquD58Ozauewf7DD14rsN0Dj7moe3gFVCovcv_v6_aj1r6m5kElCYH9AdcYlTU</recordid><startdate>20040701</startdate><enddate>20040701</enddate><creator>HASHIMOTO, Shu</creator><creator>KURAMOCHI, Takashi</creator><creator>AOYAGI, Kazuki</creator><creator>TAKAHASHI, Ri-ichi</creator><creator>UEDA, Masatsugu</creator><creator>HIRAO, Masao</creator><creator>KAMEI, Mikako</creator><creator>KITADA, Kensaku</creator><creator>HIRASAWA, Kazuo</creator><general>Japanese Association for Laboratory Animal Science</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20040701</creationdate><title>Refined Porcine Follicle Stimulating Hormone Promotes the Responsiveness of Rabbits to Multiple-Ovulation Treatment</title><author>HASHIMOTO, Shu ; KURAMOCHI, Takashi ; AOYAGI, Kazuki ; TAKAHASHI, Ri-ichi ; UEDA, Masatsugu ; HIRAO, Masao ; KAMEI, Mikako ; KITADA, Kensaku ; HIRASAWA, Kazuo</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c563t-b937be3596974d541d05c5f220e261b82dd799c43811d1c0d3bb22dc1b5ba6593</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2004</creationdate><topic>Animals</topic><topic>Female</topic><topic>Follicle Stimulating Hormone - isolation & purification</topic><topic>Follicle Stimulating Hormone - pharmacology</topic><topic>follicle-stimulating hormone</topic><topic>multiple-ovulation</topic><topic>Ovulation - drug effects</topic><topic>Pregnancy</topic><topic>Rabbits</topic><topic>Superovulation - physiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>HASHIMOTO, Shu</creatorcontrib><creatorcontrib>KURAMOCHI, Takashi</creatorcontrib><creatorcontrib>AOYAGI, Kazuki</creatorcontrib><creatorcontrib>TAKAHASHI, Ri-ichi</creatorcontrib><creatorcontrib>UEDA, Masatsugu</creatorcontrib><creatorcontrib>HIRAO, Masao</creatorcontrib><creatorcontrib>KAMEI, Mikako</creatorcontrib><creatorcontrib>KITADA, Kensaku</creatorcontrib><creatorcontrib>HIRASAWA, Kazuo</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Experimental Animals</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>HASHIMOTO, Shu</au><au>KURAMOCHI, Takashi</au><au>AOYAGI, Kazuki</au><au>TAKAHASHI, Ri-ichi</au><au>UEDA, Masatsugu</au><au>HIRAO, Masao</au><au>KAMEI, Mikako</au><au>KITADA, Kensaku</au><au>HIRASAWA, Kazuo</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Refined Porcine Follicle Stimulating Hormone Promotes the Responsiveness of Rabbits to Multiple-Ovulation Treatment</atitle><jtitle>Experimental Animals</jtitle><addtitle>Exp Anim</addtitle><date>2004-07-01</date><risdate>2004</risdate><volume>53</volume><issue>4</issue><spage>395</spage><epage>397</epage><pages>395-397</pages><issn>1341-1357</issn><eissn>1881-7122</eissn><abstract>We investigated whether refined follicle stimulating hormone (FSH) with only a little contaminating LH can promote the responsiveness of rabbits to multiple-ovulation treatment. One group of female rabbits was stimulated with refined porcine FSH (pFSH), an FSH source with low LH activity, and another group was treated with pFSH. The mean number of eggs recovered from donors stimulated with refined pFSH (27 ± 3) was significantly greater (P<0.05) than that with pFSH (20 ± 2). Furthermore, the mean number of remaining follicles of donors stimulated with refined pFSH (19 ± 4) was significantly greater (P<0.05) than that with pFSH (12 ± 1). To decrease the number of remaining follicles in donors treated with refined pFSH, the dose of human chorionic gonadotropin (hCG) was increased from 75 to 150. However, there were no differences in the numbers of eggs and remaining follicles. The results of the present study suggest that refined pFSH with little contaminating LH promotes the responsiveness of rabbits to multiple-ovulation treatment compared with pFSH.</abstract><cop>Japan</cop><pub>Japanese Association for Laboratory Animal Science</pub><pmid>15297716</pmid><doi>10.1538/expanim.53.395</doi><tpages>3</tpages><oa>free_for_read</oa></addata></record> |
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source | J-STAGE Free; MEDLINE; EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection |
subjects | Animals Female Follicle Stimulating Hormone - isolation & purification Follicle Stimulating Hormone - pharmacology follicle-stimulating hormone multiple-ovulation Ovulation - drug effects Pregnancy Rabbits Superovulation - physiology |
title | Refined Porcine Follicle Stimulating Hormone Promotes the Responsiveness of Rabbits to Multiple-Ovulation Treatment |
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