Thyroid hormone regulation of prohormone convertase 1 (PC1): regional expression in rat brain and in vitro characterization of negative thyroid hormone response elements

Most pro-neuropeptides are processed by the prohormone convertases, PC1 and PC2. We previously reported that changes in thyroid status altered anterior pituitary PC1 mRNA and this regulation was due to triiodothyronine (T(3))-dependent interaction of thyroid hormone receptor (TR) with negative thyro...

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Veröffentlicht in:	Journal of molecular endocrinology 2004-08, Vol.33 (1), p.21-33
Hauptverfasser:	Shen, X, Li, QL, Brent, GA, Friedman, TC
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Base Sequence Brain - enzymology Cell Line Electrophoretic Mobility Shift Assay Humans In Situ Hybridization In Vitro Techniques Male Promoter Regions, Genetic Proprotein Convertase 1 - genetics Proprotein Convertase 1 - metabolism Rats Reverse Transcriptase Polymerase Chain Reaction Thyroid Hormones - physiology
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