Structure of the hepatocyte nuclear factor 6alpha and its interaction with DNA

Hepatocyte nuclear factor 6 (HNF-6) belongs to the family of One Cut transcription factors (also known as OC-1) and is essential for the development of the mouse pancreas, gall bladder, and the interhepatic bile ducts. HNF-6 binds to DNA as a monomer utilizing a single cut domain and a divergent hom...

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Veröffentlicht in:	The Journal of biological chemistry 2004-08, Vol.279 (32), p.33928-33936
Hauptverfasser:	Sheng, Wanyun, Yan, Hong, Rausa, 3rd, Francisco M, Costa, Robert H, Liao, Xiubei
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetyltransferases - metabolism Amino Acid Sequence Animals Binding Sites Cyclic AMP Response Element-Binding Protein - metabolism DNA - metabolism DNA-Binding Proteins Hepatocyte Nuclear Factor 1 Hepatocyte Nuclear Factor 1-alpha Hepatocyte Nuclear Factor 6 Histone Acetyltransferases Homeodomain Proteins - chemistry Homeodomain Proteins - genetics Homeodomain Proteins - metabolism Magnetic Resonance Spectroscopy Mice Models, Molecular Molecular Sequence Data Molecular Structure Nuclear Proteins Octamer Transcription Factor-6 Protein Folding Sequence Homology Solutions Trans-Activators - chemistry Trans-Activators - genetics Trans-Activators - metabolism Transcription Factors - chemistry
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