Synaptic Plasticity and Translation Initiation

It is widely accepted that protein synthesis, including local protein synthesis at synapses, is required for several forms of synaptic plasticity. Local protein synthesis enables synapses to control synaptic strength independent of the cell body via rapid protein production from pre-existing mRNA. T...

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Veröffentlicht in:	Learning & memory (Cold Spring Harbor, N.Y.) N.Y.), 2004-07, Vol.11 (4), p.365-372
Hauptverfasser:	Klann, Eric, Antion, Marcia D, Banko, Jessica L, Hou, Lingfei
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals DNA-Binding Proteins - genetics DNA-Binding Proteins - metabolism Fragile X Mental Retardation Protein Genetics Humans Long Term Memory Mental Retardation Mice Nerve Tissue Proteins - metabolism Neuronal Plasticity - genetics Neuronal Plasticity - physiology Neurons - physiology Peptide Initiation Factors - metabolism Protein Biosynthesis - physiology Ribosomal Protein S6 Kinases - metabolism RNA 5' Terminal Oligopyrimidine Sequence - physiology RNA, Messenger - metabolism RNA-Binding Proteins - metabolism Signal Transduction - genetics Signal Transduction - physiology Stimulation Synapses - genetics Synapses - physiology Synaptic Transmission - genetics Synaptic Transmission - physiology Transcription Factors - genetics Transcription Factors - metabolism Translation
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