Techniques to study amyloid fibril formation in vitro

Amyloid fibrils are ordered aggregates of peptides or proteins that are fibrillar in structure and contribute to the complications of many diseases (e.g., type 2 diabetes mellitus, Alzheimer’s disease, and primary systemic amyloidosis). These fibrils can also be prepared in vitro and there are three...

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Veröffentlicht in:	Methods (San Diego, Calif.) Calif.), 2004-09, Vol.34 (1), p.151-160
1. Verfasser:	Nilsson, Melanie R
Format:	Artikel
Sprache:	eng
Schlagworte:	Amyloid - chemistry Amyloid - classification Amyloid - ultrastructure Amyloid fibrils Classification Congo Red Congo Red - chemistry Criteria FTIR Microscopy, Electron, Scanning Transmission - methods Protein aggregation Protein Structure, Secondary Review Spectroscopy, Fourier Transform Infrared - methods Techniques TEM Thioflavin T
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