Risk Factors for Proximal Humerus Fracture
This case-control study of proximal humerus fracture included 448 incident female and male cases and 2,023 controls aged 45 years or older identified in five Northern California Kaiser Permanente Medical Centers in 1996–2001. Data were collected by using an interviewer-administered questionnaire. So...
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Veröffentlicht in: | American journal of epidemiology 2004-08, Vol.160 (4), p.360-367 |
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description | This case-control study of proximal humerus fracture included 448 incident female and male cases and 2,023 controls aged 45 years or older identified in five Northern California Kaiser Permanente Medical Centers in 1996–2001. Data were collected by using an interviewer-administered questionnaire. Some factors related to low bone mass, including number of fractures since age 45 years and low dietary calcium intake, were associated with increased risks of fracture, and factors thought to protect against bone loss, such as menopausal hormone therapy and calcium carbonate tablet use, were associated with reduced risks. Fall-related risk factors included previous falls, diabetes mellitus, and difficulty walking in dim light. Possible fall-related risk factors suggested for the first time in this study were seizure medication use (adjusted odds ratio (OR) = 2.80, 95% confidence interval (CI): 1.45, 5.42), depression (OR = 1.34, 95% CI: 0.98, 1.84), almost always using a hearing aid (OR = 1.92, 95% CI: 1.12, 3.31 vs. never prescribed), and left-handedness (OR = 2.36, 95% CI: 1.51, 3.68 vs. right-handedness). Difficulty with activities of daily living and lack of physical activity tended to be associated with increased risk. Prevention of falls among frail, osteoporotic persons would likely reduce the frequency of proximal humerus fracture. |
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M. ; Sternfeld, Barbara ; Prill, Mila ; Quesenberry, Charles P. ; Sidney, Stephen</creator><creatorcontrib>Chu, Sarah P. ; Kelsey, Jennifer L. ; Keegan, Theresa H. M. ; Sternfeld, Barbara ; Prill, Mila ; Quesenberry, Charles P. ; Sidney, Stephen</creatorcontrib><description>This case-control study of proximal humerus fracture included 448 incident female and male cases and 2,023 controls aged 45 years or older identified in five Northern California Kaiser Permanente Medical Centers in 1996–2001. Data were collected by using an interviewer-administered questionnaire. Some factors related to low bone mass, including number of fractures since age 45 years and low dietary calcium intake, were associated with increased risks of fracture, and factors thought to protect against bone loss, such as menopausal hormone therapy and calcium carbonate tablet use, were associated with reduced risks. Fall-related risk factors included previous falls, diabetes mellitus, and difficulty walking in dim light. Possible fall-related risk factors suggested for the first time in this study were seizure medication use (adjusted odds ratio (OR) = 2.80, 95% confidence interval (CI): 1.45, 5.42), depression (OR = 1.34, 95% CI: 0.98, 1.84), almost always using a hearing aid (OR = 1.92, 95% CI: 1.12, 3.31 vs. never prescribed), and left-handedness (OR = 2.36, 95% CI: 1.51, 3.68 vs. right-handedness). Difficulty with activities of daily living and lack of physical activity tended to be associated with increased risk. Prevention of falls among frail, osteoporotic persons would likely reduce the frequency of proximal humerus fracture.</description><identifier>ISSN: 0002-9262</identifier><identifier>EISSN: 1476-6256</identifier><identifier>EISSN: 0002-9262</identifier><identifier>DOI: 10.1093/aje/kwh224</identifier><identifier>PMID: 15286021</identifier><identifier>CODEN: AJEPAS</identifier><language>eng</language><publisher>Cary, NC: Oxford University Press</publisher><subject>Abbreviation: BMI ; accidental falls ; Age Distribution ; Aged ; Aged, 80 and over ; Analysis. Health state ; Anthropometry ; Biological and medical sciences ; body mass index ; Calcium, Dietary - therapeutic use ; California - epidemiology ; Case studies ; Case-Control Studies ; Continental Population Groups - statistics & numerical data ; Epidemiology ; estrogen replacement therapy ; Estrogen Replacement Therapy - statistics & numerical data ; Ethnic Groups - statistics & numerical data ; Falls ; Female ; Fractures ; Functional Laterality ; General aspects ; Humans ; humerus ; Injuries of the limb. Injuries of the spine ; laterality ; Life Style ; Male ; Medical sciences ; Middle age ; Middle Aged ; Mobility ; motor activity ; Odds Ratio ; pharmaceutical preparations ; Public health. Hygiene ; Public health. Hygiene-occupational medicine ; Risk Factors ; Sex Distribution ; Shoulder Fractures - epidemiology ; Traumas. Diseases due to physical agents</subject><ispartof>American journal of epidemiology, 2004-08, Vol.160 (4), p.360-367</ispartof><rights>2004 INIST-CNRS</rights><rights>Copyright Oxford University Press(England) Aug 15, 2004</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c445t-3b2cf67602ecb37bf8cacfc92edde9602a9053bbc40e4d86e9365c23b18d6dbb3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=16076754$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15286021$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Chu, Sarah P.</creatorcontrib><creatorcontrib>Kelsey, Jennifer L.</creatorcontrib><creatorcontrib>Keegan, Theresa H. M.</creatorcontrib><creatorcontrib>Sternfeld, Barbara</creatorcontrib><creatorcontrib>Prill, Mila</creatorcontrib><creatorcontrib>Quesenberry, Charles P.</creatorcontrib><creatorcontrib>Sidney, Stephen</creatorcontrib><title>Risk Factors for Proximal Humerus Fracture</title><title>American journal of epidemiology</title><addtitle>Am. J. Epidemiol</addtitle><description>This case-control study of proximal humerus fracture included 448 incident female and male cases and 2,023 controls aged 45 years or older identified in five Northern California Kaiser Permanente Medical Centers in 1996–2001. Data were collected by using an interviewer-administered questionnaire. Some factors related to low bone mass, including number of fractures since age 45 years and low dietary calcium intake, were associated with increased risks of fracture, and factors thought to protect against bone loss, such as menopausal hormone therapy and calcium carbonate tablet use, were associated with reduced risks. Fall-related risk factors included previous falls, diabetes mellitus, and difficulty walking in dim light. Possible fall-related risk factors suggested for the first time in this study were seizure medication use (adjusted odds ratio (OR) = 2.80, 95% confidence interval (CI): 1.45, 5.42), depression (OR = 1.34, 95% CI: 0.98, 1.84), almost always using a hearing aid (OR = 1.92, 95% CI: 1.12, 3.31 vs. never prescribed), and left-handedness (OR = 2.36, 95% CI: 1.51, 3.68 vs. right-handedness). Difficulty with activities of daily living and lack of physical activity tended to be associated with increased risk. Prevention of falls among frail, osteoporotic persons would likely reduce the frequency of proximal humerus fracture.</description><subject>Abbreviation: BMI</subject><subject>accidental falls</subject><subject>Age Distribution</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Analysis. Health state</subject><subject>Anthropometry</subject><subject>Biological and medical sciences</subject><subject>body mass index</subject><subject>Calcium, Dietary - therapeutic use</subject><subject>California - epidemiology</subject><subject>Case studies</subject><subject>Case-Control Studies</subject><subject>Continental Population Groups - statistics & numerical data</subject><subject>Epidemiology</subject><subject>estrogen replacement therapy</subject><subject>Estrogen Replacement Therapy - statistics & numerical data</subject><subject>Ethnic Groups - statistics & numerical data</subject><subject>Falls</subject><subject>Female</subject><subject>Fractures</subject><subject>Functional Laterality</subject><subject>General aspects</subject><subject>Humans</subject><subject>humerus</subject><subject>Injuries of the limb. Injuries of the spine</subject><subject>laterality</subject><subject>Life Style</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle age</subject><subject>Middle Aged</subject><subject>Mobility</subject><subject>motor activity</subject><subject>Odds Ratio</subject><subject>pharmaceutical preparations</subject><subject>Public health. Hygiene</subject><subject>Public health. Hygiene-occupational medicine</subject><subject>Risk Factors</subject><subject>Sex Distribution</subject><subject>Shoulder Fractures - epidemiology</subject><subject>Traumas. Diseases due to physical agents</subject><issn>0002-9262</issn><issn>1476-6256</issn><issn>0002-9262</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkF1LwzAUQIMobk5f_AFSBH0Y1OWjSdpHGc76AY6hIL6EJE2xW7fOpMX5781sceCLL7mQezhwDwCnCF4hmJCRnJvR4vMd42gP9FHEWcgwZfugDyHEYYIZ7oEj5-YQIpRQeAh6iOKYQYz6YDgr3CKYSF1X1gV5ZYOprTbFUpZB2iyNbVwwsX7bWHMMDnJZOnPSzQF4mdw8j9Pw8en2bnz9GOooonVIFNY5415vtCJc5bGWOtcJNllmEv8tE0iJUjqCJspiZhLCqMZEoThjmVJkAC5b79pWH41xtVgWTpuylCtTNU4wL8f--RdEnFMYM-LB8z_gvGrsyh8hMKHxTxYPDVtI28o5a3Kxtr6D_RIIim1n4TuLtrOHzzpjo5Ym26FdWA9cdIB0Wpa5lStduB3HIGecbkVhyxWuNpvfvbQL4S_kVKSvbyJ94OksmUbinnwD9P-UCA</recordid><startdate>20040815</startdate><enddate>20040815</enddate><creator>Chu, Sarah P.</creator><creator>Kelsey, Jennifer L.</creator><creator>Keegan, Theresa H. M.</creator><creator>Sternfeld, Barbara</creator><creator>Prill, Mila</creator><creator>Quesenberry, Charles P.</creator><creator>Sidney, Stephen</creator><general>Oxford University Press</general><general>Oxford Publishing Limited (England)</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QP</scope><scope>7T2</scope><scope>7TK</scope><scope>7U7</scope><scope>7U9</scope><scope>C1K</scope><scope>H94</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7U1</scope><scope>7X8</scope></search><sort><creationdate>20040815</creationdate><title>Risk Factors for Proximal Humerus Fracture</title><author>Chu, Sarah P. ; Kelsey, Jennifer L. ; Keegan, Theresa H. M. ; Sternfeld, Barbara ; Prill, Mila ; Quesenberry, Charles P. ; Sidney, Stephen</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c445t-3b2cf67602ecb37bf8cacfc92edde9602a9053bbc40e4d86e9365c23b18d6dbb3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2004</creationdate><topic>Abbreviation: BMI</topic><topic>accidental falls</topic><topic>Age Distribution</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Analysis. Health state</topic><topic>Anthropometry</topic><topic>Biological and medical sciences</topic><topic>body mass index</topic><topic>Calcium, Dietary - therapeutic use</topic><topic>California - epidemiology</topic><topic>Case studies</topic><topic>Case-Control Studies</topic><topic>Continental Population Groups - statistics & numerical data</topic><topic>Epidemiology</topic><topic>estrogen replacement therapy</topic><topic>Estrogen Replacement Therapy - statistics & numerical data</topic><topic>Ethnic Groups - statistics & numerical data</topic><topic>Falls</topic><topic>Female</topic><topic>Fractures</topic><topic>Functional Laterality</topic><topic>General aspects</topic><topic>Humans</topic><topic>humerus</topic><topic>Injuries of the limb. Injuries of the spine</topic><topic>laterality</topic><topic>Life Style</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle age</topic><topic>Middle Aged</topic><topic>Mobility</topic><topic>motor activity</topic><topic>Odds Ratio</topic><topic>pharmaceutical preparations</topic><topic>Public health. Hygiene</topic><topic>Public health. Hygiene-occupational medicine</topic><topic>Risk Factors</topic><topic>Sex Distribution</topic><topic>Shoulder Fractures - epidemiology</topic><topic>Traumas. Diseases due to physical agents</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Chu, Sarah P.</creatorcontrib><creatorcontrib>Kelsey, Jennifer L.</creatorcontrib><creatorcontrib>Keegan, Theresa H. M.</creatorcontrib><creatorcontrib>Sternfeld, Barbara</creatorcontrib><creatorcontrib>Prill, Mila</creatorcontrib><creatorcontrib>Quesenberry, Charles P.</creatorcontrib><creatorcontrib>Sidney, Stephen</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Health and Safety Science Abstracts (Full archive)</collection><collection>Neurosciences Abstracts</collection><collection>Toxicology Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><collection>Risk Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>American journal of epidemiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chu, Sarah P.</au><au>Kelsey, Jennifer L.</au><au>Keegan, Theresa H. M.</au><au>Sternfeld, Barbara</au><au>Prill, Mila</au><au>Quesenberry, Charles P.</au><au>Sidney, Stephen</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Risk Factors for Proximal Humerus Fracture</atitle><jtitle>American journal of epidemiology</jtitle><addtitle>Am. J. Epidemiol</addtitle><date>2004-08-15</date><risdate>2004</risdate><volume>160</volume><issue>4</issue><spage>360</spage><epage>367</epage><pages>360-367</pages><issn>0002-9262</issn><eissn>1476-6256</eissn><eissn>0002-9262</eissn><coden>AJEPAS</coden><abstract>This case-control study of proximal humerus fracture included 448 incident female and male cases and 2,023 controls aged 45 years or older identified in five Northern California Kaiser Permanente Medical Centers in 1996–2001. Data were collected by using an interviewer-administered questionnaire. Some factors related to low bone mass, including number of fractures since age 45 years and low dietary calcium intake, were associated with increased risks of fracture, and factors thought to protect against bone loss, such as menopausal hormone therapy and calcium carbonate tablet use, were associated with reduced risks. Fall-related risk factors included previous falls, diabetes mellitus, and difficulty walking in dim light. Possible fall-related risk factors suggested for the first time in this study were seizure medication use (adjusted odds ratio (OR) = 2.80, 95% confidence interval (CI): 1.45, 5.42), depression (OR = 1.34, 95% CI: 0.98, 1.84), almost always using a hearing aid (OR = 1.92, 95% CI: 1.12, 3.31 vs. never prescribed), and left-handedness (OR = 2.36, 95% CI: 1.51, 3.68 vs. right-handedness). Difficulty with activities of daily living and lack of physical activity tended to be associated with increased risk. Prevention of falls among frail, osteoporotic persons would likely reduce the frequency of proximal humerus fracture.</abstract><cop>Cary, NC</cop><pub>Oxford University Press</pub><pmid>15286021</pmid><doi>10.1093/aje/kwh224</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Abbreviation: BMI accidental falls Age Distribution Aged Aged, 80 and over Analysis. Health state Anthropometry Biological and medical sciences body mass index Calcium, Dietary - therapeutic use California - epidemiology Case studies Case-Control Studies Continental Population Groups - statistics & numerical data Epidemiology estrogen replacement therapy Estrogen Replacement Therapy - statistics & numerical data Ethnic Groups - statistics & numerical data Falls Female Fractures Functional Laterality General aspects Humans humerus Injuries of the limb. Injuries of the spine laterality Life Style Male Medical sciences Middle age Middle Aged Mobility motor activity Odds Ratio pharmaceutical preparations Public health. Hygiene Public health. Hygiene-occupational medicine Risk Factors Sex Distribution Shoulder Fractures - epidemiology Traumas. Diseases due to physical agents |
title | Risk Factors for Proximal Humerus Fracture |
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