Risk Factors for Proximal Humerus Fracture

This case-control study of proximal humerus fracture included 448 incident female and male cases and 2,023 controls aged 45 years or older identified in five Northern California Kaiser Permanente Medical Centers in 1996–2001. Data were collected by using an interviewer-administered questionnaire. So...

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Veröffentlicht in:American journal of epidemiology 2004-08, Vol.160 (4), p.360-367
Hauptverfasser: Chu, Sarah P., Kelsey, Jennifer L., Keegan, Theresa H. M., Sternfeld, Barbara, Prill, Mila, Quesenberry, Charles P., Sidney, Stephen
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container_end_page 367
container_issue 4
container_start_page 360
container_title American journal of epidemiology
container_volume 160
creator Chu, Sarah P.
Kelsey, Jennifer L.
Keegan, Theresa H. M.
Sternfeld, Barbara
Prill, Mila
Quesenberry, Charles P.
Sidney, Stephen
description This case-control study of proximal humerus fracture included 448 incident female and male cases and 2,023 controls aged 45 years or older identified in five Northern California Kaiser Permanente Medical Centers in 1996–2001. Data were collected by using an interviewer-administered questionnaire. Some factors related to low bone mass, including number of fractures since age 45 years and low dietary calcium intake, were associated with increased risks of fracture, and factors thought to protect against bone loss, such as menopausal hormone therapy and calcium carbonate tablet use, were associated with reduced risks. Fall-related risk factors included previous falls, diabetes mellitus, and difficulty walking in dim light. Possible fall-related risk factors suggested for the first time in this study were seizure medication use (adjusted odds ratio (OR) = 2.80, 95% confidence interval (CI): 1.45, 5.42), depression (OR = 1.34, 95% CI: 0.98, 1.84), almost always using a hearing aid (OR = 1.92, 95% CI: 1.12, 3.31 vs. never prescribed), and left-handedness (OR = 2.36, 95% CI: 1.51, 3.68 vs. right-handedness). Difficulty with activities of daily living and lack of physical activity tended to be associated with increased risk. Prevention of falls among frail, osteoporotic persons would likely reduce the frequency of proximal humerus fracture.
doi_str_mv 10.1093/aje/kwh224
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M. ; Sternfeld, Barbara ; Prill, Mila ; Quesenberry, Charles P. ; Sidney, Stephen</creator><creatorcontrib>Chu, Sarah P. ; Kelsey, Jennifer L. ; Keegan, Theresa H. M. ; Sternfeld, Barbara ; Prill, Mila ; Quesenberry, Charles P. ; Sidney, Stephen</creatorcontrib><description>This case-control study of proximal humerus fracture included 448 incident female and male cases and 2,023 controls aged 45 years or older identified in five Northern California Kaiser Permanente Medical Centers in 1996–2001. Data were collected by using an interviewer-administered questionnaire. Some factors related to low bone mass, including number of fractures since age 45 years and low dietary calcium intake, were associated with increased risks of fracture, and factors thought to protect against bone loss, such as menopausal hormone therapy and calcium carbonate tablet use, were associated with reduced risks. Fall-related risk factors included previous falls, diabetes mellitus, and difficulty walking in dim light. Possible fall-related risk factors suggested for the first time in this study were seizure medication use (adjusted odds ratio (OR) = 2.80, 95% confidence interval (CI): 1.45, 5.42), depression (OR = 1.34, 95% CI: 0.98, 1.84), almost always using a hearing aid (OR = 1.92, 95% CI: 1.12, 3.31 vs. never prescribed), and left-handedness (OR = 2.36, 95% CI: 1.51, 3.68 vs. right-handedness). Difficulty with activities of daily living and lack of physical activity tended to be associated with increased risk. Prevention of falls among frail, osteoporotic persons would likely reduce the frequency of proximal humerus fracture.</description><identifier>ISSN: 0002-9262</identifier><identifier>EISSN: 1476-6256</identifier><identifier>EISSN: 0002-9262</identifier><identifier>DOI: 10.1093/aje/kwh224</identifier><identifier>PMID: 15286021</identifier><identifier>CODEN: AJEPAS</identifier><language>eng</language><publisher>Cary, NC: Oxford University Press</publisher><subject>Abbreviation: BMI ; accidental falls ; Age Distribution ; Aged ; Aged, 80 and over ; Analysis. 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M.</creatorcontrib><creatorcontrib>Sternfeld, Barbara</creatorcontrib><creatorcontrib>Prill, Mila</creatorcontrib><creatorcontrib>Quesenberry, Charles P.</creatorcontrib><creatorcontrib>Sidney, Stephen</creatorcontrib><title>Risk Factors for Proximal Humerus Fracture</title><title>American journal of epidemiology</title><addtitle>Am. J. Epidemiol</addtitle><description>This case-control study of proximal humerus fracture included 448 incident female and male cases and 2,023 controls aged 45 years or older identified in five Northern California Kaiser Permanente Medical Centers in 1996–2001. Data were collected by using an interviewer-administered questionnaire. Some factors related to low bone mass, including number of fractures since age 45 years and low dietary calcium intake, were associated with increased risks of fracture, and factors thought to protect against bone loss, such as menopausal hormone therapy and calcium carbonate tablet use, were associated with reduced risks. Fall-related risk factors included previous falls, diabetes mellitus, and difficulty walking in dim light. Possible fall-related risk factors suggested for the first time in this study were seizure medication use (adjusted odds ratio (OR) = 2.80, 95% confidence interval (CI): 1.45, 5.42), depression (OR = 1.34, 95% CI: 0.98, 1.84), almost always using a hearing aid (OR = 1.92, 95% CI: 1.12, 3.31 vs. never prescribed), and left-handedness (OR = 2.36, 95% CI: 1.51, 3.68 vs. right-handedness). Difficulty with activities of daily living and lack of physical activity tended to be associated with increased risk. Prevention of falls among frail, osteoporotic persons would likely reduce the frequency of proximal humerus fracture.</description><subject>Abbreviation: BMI</subject><subject>accidental falls</subject><subject>Age Distribution</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Analysis. Health state</subject><subject>Anthropometry</subject><subject>Biological and medical sciences</subject><subject>body mass index</subject><subject>Calcium, Dietary - therapeutic use</subject><subject>California - epidemiology</subject><subject>Case studies</subject><subject>Case-Control Studies</subject><subject>Continental Population Groups - statistics &amp; numerical data</subject><subject>Epidemiology</subject><subject>estrogen replacement therapy</subject><subject>Estrogen Replacement Therapy - statistics &amp; numerical data</subject><subject>Ethnic Groups - statistics &amp; numerical data</subject><subject>Falls</subject><subject>Female</subject><subject>Fractures</subject><subject>Functional Laterality</subject><subject>General aspects</subject><subject>Humans</subject><subject>humerus</subject><subject>Injuries of the limb. Injuries of the spine</subject><subject>laterality</subject><subject>Life Style</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle age</subject><subject>Middle Aged</subject><subject>Mobility</subject><subject>motor activity</subject><subject>Odds Ratio</subject><subject>pharmaceutical preparations</subject><subject>Public health. Hygiene</subject><subject>Public health. Hygiene-occupational medicine</subject><subject>Risk Factors</subject><subject>Sex Distribution</subject><subject>Shoulder Fractures - epidemiology</subject><subject>Traumas. 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Health state</topic><topic>Anthropometry</topic><topic>Biological and medical sciences</topic><topic>body mass index</topic><topic>Calcium, Dietary - therapeutic use</topic><topic>California - epidemiology</topic><topic>Case studies</topic><topic>Case-Control Studies</topic><topic>Continental Population Groups - statistics &amp; numerical data</topic><topic>Epidemiology</topic><topic>estrogen replacement therapy</topic><topic>Estrogen Replacement Therapy - statistics &amp; numerical data</topic><topic>Ethnic Groups - statistics &amp; numerical data</topic><topic>Falls</topic><topic>Female</topic><topic>Fractures</topic><topic>Functional Laterality</topic><topic>General aspects</topic><topic>Humans</topic><topic>humerus</topic><topic>Injuries of the limb. 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M.</au><au>Sternfeld, Barbara</au><au>Prill, Mila</au><au>Quesenberry, Charles P.</au><au>Sidney, Stephen</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Risk Factors for Proximal Humerus Fracture</atitle><jtitle>American journal of epidemiology</jtitle><addtitle>Am. J. Epidemiol</addtitle><date>2004-08-15</date><risdate>2004</risdate><volume>160</volume><issue>4</issue><spage>360</spage><epage>367</epage><pages>360-367</pages><issn>0002-9262</issn><eissn>1476-6256</eissn><eissn>0002-9262</eissn><coden>AJEPAS</coden><abstract>This case-control study of proximal humerus fracture included 448 incident female and male cases and 2,023 controls aged 45 years or older identified in five Northern California Kaiser Permanente Medical Centers in 1996–2001. Data were collected by using an interviewer-administered questionnaire. 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Prevention of falls among frail, osteoporotic persons would likely reduce the frequency of proximal humerus fracture.</abstract><cop>Cary, NC</cop><pub>Oxford University Press</pub><pmid>15286021</pmid><doi>10.1093/aje/kwh224</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record>
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subjects Abbreviation: BMI
accidental falls
Age Distribution
Aged
Aged, 80 and over
Analysis. Health state
Anthropometry
Biological and medical sciences
body mass index
Calcium, Dietary - therapeutic use
California - epidemiology
Case studies
Case-Control Studies
Continental Population Groups - statistics & numerical data
Epidemiology
estrogen replacement therapy
Estrogen Replacement Therapy - statistics & numerical data
Ethnic Groups - statistics & numerical data
Falls
Female
Fractures
Functional Laterality
General aspects
Humans
humerus
Injuries of the limb. Injuries of the spine
laterality
Life Style
Male
Medical sciences
Middle age
Middle Aged
Mobility
motor activity
Odds Ratio
pharmaceutical preparations
Public health. Hygiene
Public health. Hygiene-occupational medicine
Risk Factors
Sex Distribution
Shoulder Fractures - epidemiology
Traumas. Diseases due to physical agents
title Risk Factors for Proximal Humerus Fracture
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