Alternative mechanisms of gene amplification in human cancers

Gene amplification is a common phenomenon in cancer. Cytogenetic analyses have indicated that breakage‐fusion‐bridge (BFB) cycles drive intrachromosomal amplification of some oncogenes in a head‐to‐head manner in human cancers. However, the complex structures of an amplified sequence found in cancer...

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Veröffentlicht in:	Genes chromosomes & cancer 2004-10, Vol.41 (2), p.125-132
Hauptverfasser:	Kuwahara, Yoshitaka, Tanabe, Chikako, Ikeuchi, Tatsuro, Aoyagi, Kazuhiko, Nishigaki, Michiko, Sakamoto, Hiromi, Hoshinaga, Kiyotaka, Yoshida, Teruhiko, Sasaki, Hiroki, Terada, Masaaki
Format:	Artikel
Sprache:	eng
Schlagworte:	Base Sequence Blotting, Southern Cell Line, Tumor Chromosome Mapping Chromosomes, Human, Pair 17 - genetics DNA Primers Esophageal Neoplasms - genetics Female Gene Amplification - genetics Humans In Situ Hybridization, Fluorescence Neoplasms - genetics Ovarian Neoplasms - genetics Polymerase Chain Reaction Stomach Neoplasms - genetics
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