The expanded family of class II cytokines that share the IL-10 receptor-2 (IL-10R2) chain

Several novel interleukin (IL)‐10‐related cytokines have recently been discovered. These include IL‐22, IL‐26, and the interferon‐λ (IFN‐λ) proteins IFN‐λ1 (IL‐29), IFN‐λ2 (IL‐28A), and IFN‐λ3 (IL‐28B). The ligand‐binding chains for IL‐22, IL‐26, and IFN‐λ are distinct from that used by IL‐10; howev...

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Veröffentlicht in:	Journal of leukocyte biology 2004-08, Vol.76 (2), p.314-321
Hauptverfasser:	Donnelly, Raymond P., Sheikh, Faruk, Kotenko, Sergei V., Dickensheets, Harold
Format:	Artikel
Sprache:	eng
Schlagworte:	1SGF3 Animals Cytokines - metabolism hepatocytes Humans IFN‐λ IL‐22BP Interferon gamma Receptor Interleukin-10 Receptor beta Subunit Membrane Glycoproteins - metabolism Receptors, Cytokine - metabolism Receptors, Interferon - genetics Receptors, Interleukin - metabolism STAT3/STAT1
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