Trends in enzyme therapy for phenylketonuria

Phenylketonuria (PKU) is an inborn error of amino acid metabolism caused by phenylalanine hydroxylase (PAH) deficiency. Dietary treatment has been the cornerstone for controlling systemic phenylalanine (Phe) levels in PKU for the past 4 decades. Over the years, it has become clear that blood Phe con...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Molecular therapy 2004-08, Vol.10 (2), p.220-224
Hauptverfasser:	Kim, Woomi, Erlandsen, Heidi, Surendran, Sankar, Stevens, Raymond C, Gamez, Alejandra, Michols-Matalon, Kimberlee, Tyring, Stephen K, Matalon, Reuben
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acids Ammonia Biopterins - analogs & derivatives Biopterins - pharmacology Capsules - chemistry Diet Drug Therapy - methods Drug Therapy - trends Enzymes Gene therapy Humans Metabolism Mutation Oral administration Pediatrics Phenylalanine Ammonia-Lyase - chemistry Phenylalanine Ammonia-Lyase - metabolism Phenylalanine Ammonia-Lyase - therapeutic use Phenylalanine Hydroxylase - chemistry Phenylalanine Hydroxylase - metabolism Phenylalanine Hydroxylase - therapeutic use Phenylketonuria Phenylketonurias - drug therapy Phenylketonurias - metabolism Polyethylene glycol Polyethylene Glycols - chemistry Trends
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!