Cytotoxic phenylethanol glycosides from Psidium guaijava seeds
Phytochemical investigations of the acetone extract of Psidium guaijava seeds has led to the isolation of two new phenylethanoid glycosides ( 1 and 2) and their investigation for their pharmacological activity. Phytochemical investigations of the acetone extract of Psidium guaijava seeds has led to...
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Veröffentlicht in: | Phytochemistry (Oxford) 2004-07, Vol.65 (14), p.2091-2093 |
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description | Phytochemical investigations of the acetone extract of
Psidium guaijava seeds has led to the isolation of two new phenylethanoid glycosides (
1 and
2) and their investigation for their pharmacological activity.
Phytochemical investigations of the acetone extract of
Psidium guaijava seeds has led to the isolation of five known flavonoid glycosides, two phenolic glycosides and two new phenylethanoid glycosides which have been identified as 1-
O-3,4-dimethoxy-phenylethyl-4-
O-3,4-dimethoxy cinnamoyl-6-
O-cinnamoyl-β-
d-glucopyranose and 1-
O-3,4-dimethoxyphenylethyl-4-
O-3,4-dimethoxy cinnamoyl-β-
d-glucopyranose, on the basis of chemical, physical and spectroscopic methods of analysis. |
doi_str_mv | 10.1016/j.phytochem.2004.06.009 |
format | Article |
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Psidium guaijava seeds has led to the isolation of two new phenylethanoid glycosides (
1 and
2) and their investigation for their pharmacological activity.
Phytochemical investigations of the acetone extract of
Psidium guaijava seeds has led to the isolation of five known flavonoid glycosides, two phenolic glycosides and two new phenylethanoid glycosides which have been identified as 1-
O-3,4-dimethoxy-phenylethyl-4-
O-3,4-dimethoxy cinnamoyl-6-
O-cinnamoyl-β-
d-glucopyranose and 1-
O-3,4-dimethoxyphenylethyl-4-
O-3,4-dimethoxy cinnamoyl-β-
d-glucopyranose, on the basis of chemical, physical and spectroscopic methods of analysis.</description><identifier>ISSN: 0031-9422</identifier><identifier>EISSN: 1873-3700</identifier><identifier>DOI: 10.1016/j.phytochem.2004.06.009</identifier><identifier>PMID: 15279977</identifier><language>eng</language><publisher>Amsterdam: Elsevier Ltd</publisher><subject>Animals ; anticarcinogenic activity ; Biological and medical sciences ; Cell Line, Tumor ; cell lines ; Chemical constitution ; chemical structure ; cytotoxicity ; Female ; Fundamental and applied biological sciences. Psychology ; General pharmacology ; glycosides ; Glycosides - chemistry ; Glycosides - isolation & purification ; human health ; Humans ; Magnetic Resonance Spectroscopy ; Medical sciences ; medicinal plants ; medicinal properties ; Mice ; Myrtaceae ; NMR spectroscopy ; Pharmacognosy. Homeopathy. Health food ; Pharmacological activity ; Pharmacology. Drug treatments ; Phenylethanoid glycosides ; phenylethanol glycosides ; phytochemicals ; Plant physiology and development ; Psidium - chemistry ; Psidium guaijava ; Psidium guajava ; Seeds ; Seeds - chemistry ; spectral analysis ; Ultraviolet Rays</subject><ispartof>Phytochemistry (Oxford), 2004-07, Vol.65 (14), p.2091-2093</ispartof><rights>2004 Elsevier Ltd</rights><rights>2004 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c421t-22cd6f1557b4565b6d4b0d963cd90be960f63b51b1817c3b73633da4f8f5b693</citedby><cites>FETCH-LOGICAL-c421t-22cd6f1557b4565b6d4b0d963cd90be960f63b51b1817c3b73633da4f8f5b693</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.phytochem.2004.06.009$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3548,27923,27924,45994</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=16024087$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15279977$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Salib, Josline Y.</creatorcontrib><creatorcontrib>Michael, Helana N.</creatorcontrib><title>Cytotoxic phenylethanol glycosides from Psidium guaijava seeds</title><title>Phytochemistry (Oxford)</title><addtitle>Phytochemistry</addtitle><description>Phytochemical investigations of the acetone extract of
Psidium guaijava seeds has led to the isolation of two new phenylethanoid glycosides (
1 and
2) and their investigation for their pharmacological activity.
Phytochemical investigations of the acetone extract of
Psidium guaijava seeds has led to the isolation of five known flavonoid glycosides, two phenolic glycosides and two new phenylethanoid glycosides which have been identified as 1-
O-3,4-dimethoxy-phenylethyl-4-
O-3,4-dimethoxy cinnamoyl-6-
O-cinnamoyl-β-
d-glucopyranose and 1-
O-3,4-dimethoxyphenylethyl-4-
O-3,4-dimethoxy cinnamoyl-β-
d-glucopyranose, on the basis of chemical, physical and spectroscopic methods of analysis.</description><subject>Animals</subject><subject>anticarcinogenic activity</subject><subject>Biological and medical sciences</subject><subject>Cell Line, Tumor</subject><subject>cell lines</subject><subject>Chemical constitution</subject><subject>chemical structure</subject><subject>cytotoxicity</subject><subject>Female</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>General pharmacology</subject><subject>glycosides</subject><subject>Glycosides - chemistry</subject><subject>Glycosides - isolation & purification</subject><subject>human health</subject><subject>Humans</subject><subject>Magnetic Resonance Spectroscopy</subject><subject>Medical sciences</subject><subject>medicinal plants</subject><subject>medicinal properties</subject><subject>Mice</subject><subject>Myrtaceae</subject><subject>NMR spectroscopy</subject><subject>Pharmacognosy. Homeopathy. Health food</subject><subject>Pharmacological activity</subject><subject>Pharmacology. Drug treatments</subject><subject>Phenylethanoid glycosides</subject><subject>phenylethanol glycosides</subject><subject>phytochemicals</subject><subject>Plant physiology and development</subject><subject>Psidium - chemistry</subject><subject>Psidium guaijava</subject><subject>Psidium guajava</subject><subject>Seeds</subject><subject>Seeds - chemistry</subject><subject>spectral analysis</subject><subject>Ultraviolet Rays</subject><issn>0031-9422</issn><issn>1873-3700</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkMtu2zAQRYmiReO6_YVGm3YnZUiKpLQpEBh9AQFaIMmaoMiRTUMSXVIK6r8PDRvNsquZxbnzOIRcU6goUHmzrw674xzsDseKAdQVyAqgfUVWtFG85ArgNVkBcFq2NWNX5F1KewAQQsq35IoKptpWqRX5sslj5vDX2-Kww-k44LwzUxiK7XC0IXmHqehjGIvfuffLWGwX4_fmyRQJ0aX35E1vhoQfLnVNHr59fdj8KO9-ff-5ub0rbc3oXDJmneypEKqrhRSddHUHrpXcuhY6bCX0kneCdrShyvJOccm5M3Xf9Blu-Zp8Po89xPBnwTTr0SeLw2AmDEvSUiohQDYZVGfQxpBSxF4foh9NPGoK-mRO7_U_c_pkToPU2VxOfrysWLoR3UvuoioDny6ASdYMfTST9emFk8BqaE7c9ZnrTdBmGzPzeM-A8rwlH5k_W5PbM4HZ2JPHqJP1OFl0PqKdtQv-v-c-A083miI</recordid><startdate>20040701</startdate><enddate>20040701</enddate><creator>Salib, Josline Y.</creator><creator>Michael, Helana N.</creator><general>Elsevier Ltd</general><general>Elsevier</general><scope>FBQ</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20040701</creationdate><title>Cytotoxic phenylethanol glycosides from Psidium guaijava seeds</title><author>Salib, Josline Y. ; Michael, Helana N.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c421t-22cd6f1557b4565b6d4b0d963cd90be960f63b51b1817c3b73633da4f8f5b693</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2004</creationdate><topic>Animals</topic><topic>anticarcinogenic activity</topic><topic>Biological and medical sciences</topic><topic>Cell Line, Tumor</topic><topic>cell lines</topic><topic>Chemical constitution</topic><topic>chemical structure</topic><topic>cytotoxicity</topic><topic>Female</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>General pharmacology</topic><topic>glycosides</topic><topic>Glycosides - chemistry</topic><topic>Glycosides - isolation & purification</topic><topic>human health</topic><topic>Humans</topic><topic>Magnetic Resonance Spectroscopy</topic><topic>Medical sciences</topic><topic>medicinal plants</topic><topic>medicinal properties</topic><topic>Mice</topic><topic>Myrtaceae</topic><topic>NMR spectroscopy</topic><topic>Pharmacognosy. Homeopathy. Health food</topic><topic>Pharmacological activity</topic><topic>Pharmacology. Drug treatments</topic><topic>Phenylethanoid glycosides</topic><topic>phenylethanol glycosides</topic><topic>phytochemicals</topic><topic>Plant physiology and development</topic><topic>Psidium - chemistry</topic><topic>Psidium guaijava</topic><topic>Psidium guajava</topic><topic>Seeds</topic><topic>Seeds - chemistry</topic><topic>spectral analysis</topic><topic>Ultraviolet Rays</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Salib, Josline Y.</creatorcontrib><creatorcontrib>Michael, Helana N.</creatorcontrib><collection>AGRIS</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Phytochemistry (Oxford)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Salib, Josline Y.</au><au>Michael, Helana N.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Cytotoxic phenylethanol glycosides from Psidium guaijava seeds</atitle><jtitle>Phytochemistry (Oxford)</jtitle><addtitle>Phytochemistry</addtitle><date>2004-07-01</date><risdate>2004</risdate><volume>65</volume><issue>14</issue><spage>2091</spage><epage>2093</epage><pages>2091-2093</pages><issn>0031-9422</issn><eissn>1873-3700</eissn><abstract>Phytochemical investigations of the acetone extract of
Psidium guaijava seeds has led to the isolation of two new phenylethanoid glycosides (
1 and
2) and their investigation for their pharmacological activity.
Phytochemical investigations of the acetone extract of
Psidium guaijava seeds has led to the isolation of five known flavonoid glycosides, two phenolic glycosides and two new phenylethanoid glycosides which have been identified as 1-
O-3,4-dimethoxy-phenylethyl-4-
O-3,4-dimethoxy cinnamoyl-6-
O-cinnamoyl-β-
d-glucopyranose and 1-
O-3,4-dimethoxyphenylethyl-4-
O-3,4-dimethoxy cinnamoyl-β-
d-glucopyranose, on the basis of chemical, physical and spectroscopic methods of analysis.</abstract><cop>Amsterdam</cop><pub>Elsevier Ltd</pub><pmid>15279977</pmid><doi>10.1016/j.phytochem.2004.06.009</doi><tpages>3</tpages></addata></record> |
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source | MEDLINE; ScienceDirect Journals (5 years ago - present) |
subjects | Animals anticarcinogenic activity Biological and medical sciences Cell Line, Tumor cell lines Chemical constitution chemical structure cytotoxicity Female Fundamental and applied biological sciences. Psychology General pharmacology glycosides Glycosides - chemistry Glycosides - isolation & purification human health Humans Magnetic Resonance Spectroscopy Medical sciences medicinal plants medicinal properties Mice Myrtaceae NMR spectroscopy Pharmacognosy. Homeopathy. Health food Pharmacological activity Pharmacology. Drug treatments Phenylethanoid glycosides phenylethanol glycosides phytochemicals Plant physiology and development Psidium - chemistry Psidium guaijava Psidium guajava Seeds Seeds - chemistry spectral analysis Ultraviolet Rays |
title | Cytotoxic phenylethanol glycosides from Psidium guaijava seeds |
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