A PET Study of Tiagabine Treatment Implicates Ventral Medial Prefrontal Cortex in Generalized Social Anxiety Disorder

Corticolimbic circuitry has been implicated in generalized social anxiety disorder (gSAD) by several neuroimaging symptom provocation studies. However, there are limited data regarding resting state or treatment effects on regional cerebral metabolic rate of glucose uptake (rCMRglu). Given evidence...

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Veröffentlicht in:	Neuropsychopharmacology (New York, N.Y.) N.Y.), 2009-01, Vol.34 (2), p.390-398
Hauptverfasser:	EVANS, Karleyton C, SIMON, Naomi M, RAUCH, Scott L, DOUGHERTY, Darin D, HOGE, Elizabeth A, WORTHINGTON, John J, CHOW, Candice, KAUFMAN, Rebecca E, GOLD, Andrea L, FISCHMAN, Alan J, POLLACK, Mark H
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Adult and adolescent clinical studies Anxiety Anxiety Disorders - drug therapy Anxiety Disorders - physiopathology Anxiety disorders. Neuroses Biological and medical sciences Brain - diagnostic imaging Brain - metabolism Brain - physiopathology Brain Mapping Female Fluorodeoxyglucose F18 Glucose - metabolism Humans Magnetic Resonance Imaging Male Medical sciences Miscellaneous Neurotransmitter Uptake Inhibitors - administration & dosage Neurotransmitter Uptake Inhibitors - therapeutic use Nipecotic Acids - administration & dosage Nipecotic Acids - therapeutic use Phobia Positron-Emission Tomography Prefrontal Cortex - diagnostic imaging Prefrontal Cortex - drug effects Prefrontal Cortex - metabolism Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry
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