Prolonged continuous in vitro human platelet production using three-dimensional scaffolds

Objective Methods producing human platelets using growth on plastic, on feeder layers, or in suspension have been described. We hypothesized that growth of hematopoietic progenitors in a three-dimensional (3D) scaffold would enhance platelet production sans feeder layer. Materials and Methods We gre...

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Veröffentlicht in:	Experimental hematology 2009, Vol.37 (1), p.101-110
Hauptverfasser:	Sullenbarger, Brent, Bahng, Joong Hwan, Gruner, Ryan, Kotov, Nicholas, Lasky, Larry C
Format:	Artikel
Sprache:	eng
Schlagworte:	Advanced Basic Science Antigens, CD Bioreactors Blood Platelets - cytology Cell Culture Techniques Cells, Cultured Fetal Blood - cytology Hematology, Oncology and Palliative Medicine Hematopoietic Stem Cells - cytology Humans Hydrogels Time Factors
Online-Zugang:	Volltext
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