Reliability of the “immersion technique” during routine upper endoscopy for detection of abnormalities of duodenal villi in patients with dyspepsia
Upper endoscopy is not routinely performed to directly detect abnormalities of the duodenal villi. The reliability of the immersion technique for assessment of duodenal villi was evaluated in a series of patients with dyspepsia. A total of 396 patients who were to undergo standard EGD for dyspeptic...
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| Veröffentlicht in: | Gastrointestinal endoscopy 2004-08, Vol.60 (2), p.223-228 |
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| creator | Cammarota, Giovanni Pirozzi, Giuseppe A. Martino, Antonio Zuccalà, Giuseppe Cianci, Rossella Cuoco, Lucio Ojetti, Veronica Landriscina, Matteo Montalto, Massimo Vecchio, Fabio M. Gasbarrini, Giovanni Gasbarrini, Antonio |
| description | Upper endoscopy is not routinely performed to directly detect abnormalities of the duodenal villi. The reliability of the immersion technique for assessment of duodenal villi was evaluated in a series of patients with dyspepsia.
A total of 396 patients who were to undergo standard EGD for dyspeptic symptoms were enrolled. Patients with suspected malabsorption were excluded. By performing a “modified immersion technique,” duodenal villi were scored as the following: definitely present, partially present, or definitely absent. Three duodenal biopsy specimens were obtained from each patient, and villi also were scored histologically as the following: normal, partial villous pattern, or total villous atrophy.
Sensitivity, specificity, and positive and negative predictive values of the modified immersion technique for detection of total villous atrophy were 100%, 99.7%, 85.7%, and 100%, respectively. Sensitivity, specificity, and positive and negative predictive values of modified immersion technique for detection of partial villous patterns were 75%, 99.5%, 60%, and 99.7%, respectively. Sensitivity, specificity, and positive and negative predictive values for modified immersion technique detection of any villous abnormality (partial or total villous atrophy) were 90.9%, 99.5%, 83.3%, and 99.7%, respectively.
During standard EGD, duodenal evaluation by modified immersion technique can reliably detect abnormalities of duodenal villi. This simple diagnostic technique may be performed routinely during endoscopic exploration of duodenum. |
| doi_str_mv | 10.1016/S0016-5107(04)01553-6 |
| format | Article |
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A total of 396 patients who were to undergo standard EGD for dyspeptic symptoms were enrolled. Patients with suspected malabsorption were excluded. By performing a “modified immersion technique,” duodenal villi were scored as the following: definitely present, partially present, or definitely absent. Three duodenal biopsy specimens were obtained from each patient, and villi also were scored histologically as the following: normal, partial villous pattern, or total villous atrophy.
Sensitivity, specificity, and positive and negative predictive values of the modified immersion technique for detection of total villous atrophy were 100%, 99.7%, 85.7%, and 100%, respectively. Sensitivity, specificity, and positive and negative predictive values of modified immersion technique for detection of partial villous patterns were 75%, 99.5%, 60%, and 99.7%, respectively. Sensitivity, specificity, and positive and negative predictive values for modified immersion technique detection of any villous abnormality (partial or total villous atrophy) were 90.9%, 99.5%, 83.3%, and 99.7%, respectively.
During standard EGD, duodenal evaluation by modified immersion technique can reliably detect abnormalities of duodenal villi. This simple diagnostic technique may be performed routinely during endoscopic exploration of duodenum.</description><identifier>ISSN: 0016-5107</identifier><identifier>EISSN: 1097-6779</identifier><identifier>DOI: 10.1016/S0016-5107(04)01553-6</identifier><identifier>PMID: 15278049</identifier><identifier>CODEN: GAENBQ</identifier><language>eng</language><publisher>New York, NY: Mosby, Inc</publisher><subject>Atrophy ; Biological and medical sciences ; Celiac Disease - pathology ; Duodenum - pathology ; Dyspepsia - pathology ; Endoscopy, Digestive System - methods ; Female ; Gastroenterology. Liver. Pancreas. Abdomen ; Humans ; Immersion ; Male ; Medical sciences ; Other diseases. Semiology ; Predictive Value of Tests ; Reproducibility of Results ; Sensitivity and Specificity ; Stomach. Duodenum. Small intestine. Colon. Rectum. Anus</subject><ispartof>Gastrointestinal endoscopy, 2004-08, Vol.60 (2), p.223-228</ispartof><rights>2004 American Society for Gastrointestinal Endoscopy</rights><rights>2004 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c391t-6e8731d808a42ca5c95cc95ee30b00c14403e99dbf5c748343cc929d6e5df1493</citedby><cites>FETCH-LOGICAL-c391t-6e8731d808a42ca5c95cc95ee30b00c14403e99dbf5c748343cc929d6e5df1493</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/S0016-5107(04)01553-6$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=16032939$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15278049$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Cammarota, Giovanni</creatorcontrib><creatorcontrib>Pirozzi, Giuseppe A.</creatorcontrib><creatorcontrib>Martino, Antonio</creatorcontrib><creatorcontrib>Zuccalà, Giuseppe</creatorcontrib><creatorcontrib>Cianci, Rossella</creatorcontrib><creatorcontrib>Cuoco, Lucio</creatorcontrib><creatorcontrib>Ojetti, Veronica</creatorcontrib><creatorcontrib>Landriscina, Matteo</creatorcontrib><creatorcontrib>Montalto, Massimo</creatorcontrib><creatorcontrib>Vecchio, Fabio M.</creatorcontrib><creatorcontrib>Gasbarrini, Giovanni</creatorcontrib><creatorcontrib>Gasbarrini, Antonio</creatorcontrib><title>Reliability of the “immersion technique” during routine upper endoscopy for detection of abnormalities of duodenal villi in patients with dyspepsia</title><title>Gastrointestinal endoscopy</title><addtitle>Gastrointest Endosc</addtitle><description>Upper endoscopy is not routinely performed to directly detect abnormalities of the duodenal villi. The reliability of the immersion technique for assessment of duodenal villi was evaluated in a series of patients with dyspepsia.
A total of 396 patients who were to undergo standard EGD for dyspeptic symptoms were enrolled. Patients with suspected malabsorption were excluded. By performing a “modified immersion technique,” duodenal villi were scored as the following: definitely present, partially present, or definitely absent. Three duodenal biopsy specimens were obtained from each patient, and villi also were scored histologically as the following: normal, partial villous pattern, or total villous atrophy.
Sensitivity, specificity, and positive and negative predictive values of the modified immersion technique for detection of total villous atrophy were 100%, 99.7%, 85.7%, and 100%, respectively. Sensitivity, specificity, and positive and negative predictive values of modified immersion technique for detection of partial villous patterns were 75%, 99.5%, 60%, and 99.7%, respectively. Sensitivity, specificity, and positive and negative predictive values for modified immersion technique detection of any villous abnormality (partial or total villous atrophy) were 90.9%, 99.5%, 83.3%, and 99.7%, respectively.
During standard EGD, duodenal evaluation by modified immersion technique can reliably detect abnormalities of duodenal villi. This simple diagnostic technique may be performed routinely during endoscopic exploration of duodenum.</description><subject>Atrophy</subject><subject>Biological and medical sciences</subject><subject>Celiac Disease - pathology</subject><subject>Duodenum - pathology</subject><subject>Dyspepsia - pathology</subject><subject>Endoscopy, Digestive System - methods</subject><subject>Female</subject><subject>Gastroenterology. Liver. Pancreas. Abdomen</subject><subject>Humans</subject><subject>Immersion</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Other diseases. Semiology</subject><subject>Predictive Value of Tests</subject><subject>Reproducibility of Results</subject><subject>Sensitivity and Specificity</subject><subject>Stomach. Duodenum. Small intestine. Colon. Rectum. Anus</subject><issn>0016-5107</issn><issn>1097-6779</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkU2O1DAQhSMEYpqBI4C8AcEiUG7HSbwaoRF_0khI_Kwtx67QhRI72Mmg3s0t2MDl5iQ40y1mycK25Ppelf1eUTzm8JIDr199hryXkkPzHKoXwKUUZX2n2HBQTVk3jbpbbP4hJ8WDlL4DQLsV_H5xwuW2aaFSm-LXJxzIdDTQvGehZ_MO2fXVbxpHjImCZzPanacfC15f_WFuieS_sRiWmTyyZZowMvQuJBumPetDZA6zYl6VuZvpfIijyc0J03rhluDQm4Fd0jAQI88mk2t-TuwnzTvm9mnCKZF5WNzrzZDw0fE8Lb6-ffPl_H158fHdh_PXF6UVis9ljW0juGuhNdXWGmmVtHkhCugALK8qEKiU63ppm6oVlcjlrXI1StfzSonT4tmh7xRD_mSa9UjJ4jAYj2FJuq4byQWsoDyANoaUIvZ6ijSauNcc9JqIvklEr3ZrqPRNIrrOuifHAUs3ortVHSPIwNMjYJI1Qx-Nt5RuuRrEVomVOztwmO24JIw62eycRUcxO65doP885S_A562G</recordid><startdate>20040801</startdate><enddate>20040801</enddate><creator>Cammarota, Giovanni</creator><creator>Pirozzi, Giuseppe A.</creator><creator>Martino, Antonio</creator><creator>Zuccalà, Giuseppe</creator><creator>Cianci, Rossella</creator><creator>Cuoco, Lucio</creator><creator>Ojetti, Veronica</creator><creator>Landriscina, Matteo</creator><creator>Montalto, Massimo</creator><creator>Vecchio, Fabio M.</creator><creator>Gasbarrini, Giovanni</creator><creator>Gasbarrini, Antonio</creator><general>Mosby, Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20040801</creationdate><title>Reliability of the “immersion technique” during routine upper endoscopy for detection of abnormalities of duodenal villi in patients with dyspepsia</title><author>Cammarota, Giovanni ; Pirozzi, Giuseppe A. ; Martino, Antonio ; Zuccalà, Giuseppe ; Cianci, Rossella ; Cuoco, Lucio ; Ojetti, Veronica ; Landriscina, Matteo ; Montalto, Massimo ; Vecchio, Fabio M. ; Gasbarrini, Giovanni ; Gasbarrini, Antonio</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c391t-6e8731d808a42ca5c95cc95ee30b00c14403e99dbf5c748343cc929d6e5df1493</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2004</creationdate><topic>Atrophy</topic><topic>Biological and medical sciences</topic><topic>Celiac Disease - pathology</topic><topic>Duodenum - pathology</topic><topic>Dyspepsia - pathology</topic><topic>Endoscopy, Digestive System - methods</topic><topic>Female</topic><topic>Gastroenterology. Liver. Pancreas. Abdomen</topic><topic>Humans</topic><topic>Immersion</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Other diseases. Semiology</topic><topic>Predictive Value of Tests</topic><topic>Reproducibility of Results</topic><topic>Sensitivity and Specificity</topic><topic>Stomach. Duodenum. Small intestine. Colon. Rectum. Anus</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Cammarota, Giovanni</creatorcontrib><creatorcontrib>Pirozzi, Giuseppe A.</creatorcontrib><creatorcontrib>Martino, Antonio</creatorcontrib><creatorcontrib>Zuccalà, Giuseppe</creatorcontrib><creatorcontrib>Cianci, Rossella</creatorcontrib><creatorcontrib>Cuoco, Lucio</creatorcontrib><creatorcontrib>Ojetti, Veronica</creatorcontrib><creatorcontrib>Landriscina, Matteo</creatorcontrib><creatorcontrib>Montalto, Massimo</creatorcontrib><creatorcontrib>Vecchio, Fabio M.</creatorcontrib><creatorcontrib>Gasbarrini, Giovanni</creatorcontrib><creatorcontrib>Gasbarrini, Antonio</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Gastrointestinal endoscopy</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Cammarota, Giovanni</au><au>Pirozzi, Giuseppe A.</au><au>Martino, Antonio</au><au>Zuccalà, Giuseppe</au><au>Cianci, Rossella</au><au>Cuoco, Lucio</au><au>Ojetti, Veronica</au><au>Landriscina, Matteo</au><au>Montalto, Massimo</au><au>Vecchio, Fabio M.</au><au>Gasbarrini, Giovanni</au><au>Gasbarrini, Antonio</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Reliability of the “immersion technique” during routine upper endoscopy for detection of abnormalities of duodenal villi in patients with dyspepsia</atitle><jtitle>Gastrointestinal endoscopy</jtitle><addtitle>Gastrointest Endosc</addtitle><date>2004-08-01</date><risdate>2004</risdate><volume>60</volume><issue>2</issue><spage>223</spage><epage>228</epage><pages>223-228</pages><issn>0016-5107</issn><eissn>1097-6779</eissn><coden>GAENBQ</coden><abstract>Upper endoscopy is not routinely performed to directly detect abnormalities of the duodenal villi. The reliability of the immersion technique for assessment of duodenal villi was evaluated in a series of patients with dyspepsia.
A total of 396 patients who were to undergo standard EGD for dyspeptic symptoms were enrolled. Patients with suspected malabsorption were excluded. By performing a “modified immersion technique,” duodenal villi were scored as the following: definitely present, partially present, or definitely absent. Three duodenal biopsy specimens were obtained from each patient, and villi also were scored histologically as the following: normal, partial villous pattern, or total villous atrophy.
Sensitivity, specificity, and positive and negative predictive values of the modified immersion technique for detection of total villous atrophy were 100%, 99.7%, 85.7%, and 100%, respectively. Sensitivity, specificity, and positive and negative predictive values of modified immersion technique for detection of partial villous patterns were 75%, 99.5%, 60%, and 99.7%, respectively. Sensitivity, specificity, and positive and negative predictive values for modified immersion technique detection of any villous abnormality (partial or total villous atrophy) were 90.9%, 99.5%, 83.3%, and 99.7%, respectively.
During standard EGD, duodenal evaluation by modified immersion technique can reliably detect abnormalities of duodenal villi. This simple diagnostic technique may be performed routinely during endoscopic exploration of duodenum.</abstract><cop>New York, NY</cop><pub>Mosby, Inc</pub><pmid>15278049</pmid><doi>10.1016/S0016-5107(04)01553-6</doi><tpages>6</tpages></addata></record> |
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| subjects | Atrophy Biological and medical sciences Celiac Disease - pathology Duodenum - pathology Dyspepsia - pathology Endoscopy, Digestive System - methods Female Gastroenterology. Liver. Pancreas. Abdomen Humans Immersion Male Medical sciences Other diseases. Semiology Predictive Value of Tests Reproducibility of Results Sensitivity and Specificity Stomach. Duodenum. Small intestine. Colon. Rectum. Anus |
| title | Reliability of the “immersion technique” during routine upper endoscopy for detection of abnormalities of duodenal villi in patients with dyspepsia |
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