UDP-Glucose pyrophosphorylase is upregulated in carriers of the porcine RN− mutation in the AMP-activated protein kinase

The AMP‐activated protein kinase (AMPK) plays a key role in the regulation of energy metabolism in eukaryotic cells acting as a metabolic sensor. In its activated form AMPK inhibits ATP consuming pathways and stimulates ATP generating pathways. A dominant mutation, denoted RN−, in the porcine PRKAG3...

Ausführliche Beschreibung