In Situ Respiration and Bioenergetic Status of Mitochondria in Primary Cerebellar Granule Neuronal Cultures Exposed Continuously to Glutamate

Mitochondria play a central role in neuronal death during pathological exposure to glutamate (excitotoxicity). To investigate the detailed bioenergetics of the in situ mitochondria, a method is described to monitor continuously the respiration of primary cerebellar granule neuron cultures while simu...

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Veröffentlicht in:The Journal of biological chemistry 2004-07, Vol.279 (31), p.32989-33000
Hauptverfasser: Jekabsons, Mika B, Nicholls, David G
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Sprache:eng
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