Loss of PKC-delta alters cardiac metabolism

PKC-delta is believed to play an essential role in cardiomyocyte growth. In the present study, we investigated the effect of PKC-delta on cardiac metabolism using PKC-delta knockout mice generated in our laboratories. Proteomic analysis of heart protein extracts revealed profound changes in enzymes...

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Veröffentlicht in:	American journal of physiology. Heart and circulatory physiology 2004-08, Vol.287 (2), p.H937-H945
Hauptverfasser:	Mayr, Manuel, Chung, Yuen-Li, Mayr, Ursula, McGregor, Emma, Troy, Helen, Baier, Gottfried, Leitges, Michael, Dunn, Michael J, Griffiths, John R, Xu, Qingbo
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Magnetic Resonance Spectroscopy Mice Mice, Knockout Molecular Chaperones - metabolism Myocardium - enzymology Myocardium - metabolism Peroxidases - metabolism Peroxiredoxins Protein Kinase C - deficiency Protein Kinase C - physiology Protein Kinase C-delta Proteome - metabolism
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