Mechanical Strain Delivers Anti-apoptotic and Proliferative Signals to Gingival Fibroblasts

Physical forces play a critical role in the survival and proliferation of many cell types, including fibroblasts. Gingival fibroblasts are exposed to mechanical stress during mastication, orthodontic tooth movement, and wound healing following periodontal surgery. The aim of this study was to examin...

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Veröffentlicht in:	Journal of dental research 2004-08, Vol.83 (8), p.596-601
Hauptverfasser:	Danciu, T.E., Gagari, E., Adam, R.M., Damoulis, P.D., Freeman, M.R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis - physiology Cell Division - physiology Cell Size - physiology Cells, Cultured Dentistry DNA-Binding Proteins - metabolism Fibroblasts - metabolism Forkhead Box Protein O1 Forkhead Transcription Factors Gingiva - cytology Gingiva - metabolism Humans Mastication Mitogen-Activated Protein Kinases - metabolism Proliferating Cell Nuclear Antigen - metabolism Protein-Serine-Threonine Kinases - metabolism Proto-Oncogene Proteins - metabolism Proto-Oncogene Proteins c-akt Signal Transduction - physiology Stress, Mechanical Time Factors Transcription Factors - metabolism Translocation, Genetic
Online-Zugang:	Volltext
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