CLN3L, a novel protein related to the Batten disease protein, is overexpressed in Cln3−/− mice and in Batten disease

Batten disease is a severe autosomal recessive neurodegenerative disease which results from mutations in CLN3. Although the gene was cloned in 1995, the tissue distribution and subcellular localization of the CLN3 protein (CLN3P) remains inconclusive. We have demonstrated the presence of a novel 33...

Ausführliche Beschreibung