The detection of IgG and IgA autoantibodies to desmocollins 1-3 by enzyme-linked immunosorbent assays using baculovirus-expressed proteins, in atypical pemphigus but not in typical pemphigus

Summary Background We have shown previously that human desmocollin (Dsc) 1 is recognized by IgA autoantibodies of subcorneal pustular dermatosis (SPD) type IgA pemphigus. However, the presence of IgG anti‐Dsc autoantibodies is still controversial, and antibodies to Dsc2 and Dsc3 have not been clear...

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Veröffentlicht in:	British journal of dermatology (1951) 2004-07, Vol.151 (1), p.73-83
Hauptverfasser:	Hisamatsu, Y., Amagai, M., Garrod, D.R., Kanzaki, T., Hashimoto, T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Animals Autoantibodies - analysis Autoantibodies - isolation & purification Biological and medical sciences Bullous diseases of the skin Case-Control Studies Child COS Cells Cytoskeletal Proteins - immunology Dermatology desmocollin Desmocollins desmoglein Desmoplakins desmosome enzyme-linked immunosorbent assay Enzyme-Linked Immunosorbent Assay - methods Female Fluorescent Antibody Technique Humans IgA pemphigus Immunoglobulin A - immunology Immunoglobulin G - immunology Male Medical sciences Membrane Glycoproteins - immunology Middle Aged Pemphigus - immunology Rabbits
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