Effect of Akt overexpression on programmed cell death in antibody-producing Chinese hamster ovary cells
Upon nutrient deprivation, Chinese hamster ovary (CHO) cells are subjected to two types of programmed cell death, apoptosis and autophagy. CHO cell engineering, as a means to improve foreign protein production, has focused mainly on anti-apoptosis. In this study, to determine the effect of Akt, whic...
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Veröffentlicht in: | Journal of biotechnology 2009, Vol.139 (1), p.89-94 |
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Format: | Artikel |
Sprache: | eng |
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