Effect of Akt overexpression on programmed cell death in antibody-producing Chinese hamster ovary cells

Upon nutrient deprivation, Chinese hamster ovary (CHO) cells are subjected to two types of programmed cell death, apoptosis and autophagy. CHO cell engineering, as a means to improve foreign protein production, has focused mainly on anti-apoptosis. In this study, to determine the effect of Akt, whic...

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Veröffentlicht in:Journal of biotechnology 2009, Vol.139 (1), p.89-94
Hauptverfasser: Hwang, Sun Ok, Lee, Gyun Min
Format: Artikel
Sprache:eng
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