The relation between the estimated dietary intake of PCDD/Fs and levels in blood in a Flemish population (50–65 years)
Dioxin-like activity was measured in the serum of 1425 Flemish men and women via the CALUX assay. The adults, aged between 50 and 65 years, participated in a large biomonitoring program, executed by the Flemish Center of Expertise for Environment and Health between 2002 and 2006. Within the context...
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Veröffentlicht in: | Environment international 2009, Vol.35 (1), p.9-13 |
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creator | Bilau, Maaike De Henauw, Stefaan Schroijen, Carmen Bruckers, Liesbeth Hond, Elly Den Koppen, Gudrun Matthys, Christophe Van De Mieroop, Els Keune, Hans Baeyens, Willy Nelen, Vera Van Larebeke, Nik Willems, Jan L. Schoeters, Greet |
description | Dioxin-like activity was measured in the serum of 1425 Flemish men and women via the CALUX assay. The adults, aged between 50 and 65 years, participated in a large biomonitoring program, executed by the Flemish Center of Expertise for Environment and Health between 2002 and 2006. Within the context of this biomonitoring program also dietary intake of dioxin-like contaminants was assessed through a food frequency questionnaire.
The relation between the estimated dietary intake and the dioxin-like activity in serum was evaluated using multivariate analyses: a logistic model was performed on the total population, while a linear regression analysis was done on the subsample with quantifiable dioxin activity levels in serum. Region, gender, age, BMI, smoking status, as well as dietary habits were entered in the model, with dioxin level as an outcome estimate.
Both the logistic and linear model confirmed the contribution of dietary intake to the dioxin activity measured in serum. Also BMI and region were found to be associated with dioxin activity levels. |
doi_str_mv | 10.1016/j.envint.2008.05.007 |
format | Article |
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The relation between the estimated dietary intake and the dioxin-like activity in serum was evaluated using multivariate analyses: a logistic model was performed on the total population, while a linear regression analysis was done on the subsample with quantifiable dioxin activity levels in serum. Region, gender, age, BMI, smoking status, as well as dietary habits were entered in the model, with dioxin level as an outcome estimate.
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The relation between the estimated dietary intake and the dioxin-like activity in serum was evaluated using multivariate analyses: a logistic model was performed on the total population, while a linear regression analysis was done on the subsample with quantifiable dioxin activity levels in serum. Region, gender, age, BMI, smoking status, as well as dietary habits were entered in the model, with dioxin level as an outcome estimate.
Both the logistic and linear model confirmed the contribution of dietary intake to the dioxin activity measured in serum. Also BMI and region were found to be associated with dioxin activity levels.</description><subject>Aged</subject><subject>Belgium</subject><subject>Biological and medical sciences</subject><subject>Biomonitoring</subject><subject>Blood Chemical Analysis</subject><subject>CALUX</subject><subject>Dioxin-like contaminants</subject><subject>Environmental pollutants toxicology</subject><subject>Female</subject><subject>FFQ</subject><subject>Flanders</subject><subject>General aspects</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Multivariate Analysis</subject><subject>Polychlorinated Dibenzodioxins - analogs & derivatives</subject><subject>Polychlorinated Dibenzodioxins - blood</subject><subject>Polychlorinated Dibenzodioxins - metabolism</subject><subject>Risk Factors</subject><subject>Surveys and Questionnaires</subject><subject>Toxicology</subject><issn>0160-4120</issn><issn>1873-6750</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kMFu1DAQhi1ERZfCGyDkCwgOScdObCcXJLRloVIlOJSz5dgT1Us2Xuzsor3xDrwAz9JH6ZPg1UZw4-SR_c3vmY-QFwxKBkxerksc936cSg7QlCBKAPWILFijqkIqAY_JImNQ1IzDOXma0hoAeN2IJ-ScNRI4E-2CHG7vkEYczOTDSDucfiCOdMqXmCa_MRM66jxOJh5o_sx8Qxp6-mV5dXW5StSMjg64xyHlR9oNIbhjYehqwI1Pd3Qbtrs5-42Ah5-_pLj_fUAT09tn5Kw3Q8Ln83lBvq4-3C4_FTefP14v398UtmphKiS4FpUyCiU3KGxXVYpZ6WTtOKu4cCiYtQ0KYXnVtsCEaSzvHKq-74SF6oK8PuVuY_i-y1vpPJnFYTAjhl3SUqpK1KrKYH0CbQwpRez1NmYD8aAZ6KNyvdYn5fqoXIPQWXlueznn77oNun9Ns-MMvJoBk6wZ-mhG69NfjjMQTDGRuXcnLuvEvceok_U4WnQ-op20C_7_k_wBR72imw</recordid><startdate>2009</startdate><enddate>2009</enddate><creator>Bilau, Maaike</creator><creator>De Henauw, Stefaan</creator><creator>Schroijen, Carmen</creator><creator>Bruckers, Liesbeth</creator><creator>Hond, Elly Den</creator><creator>Koppen, Gudrun</creator><creator>Matthys, Christophe</creator><creator>Van De Mieroop, Els</creator><creator>Keune, Hans</creator><creator>Baeyens, Willy</creator><creator>Nelen, Vera</creator><creator>Van Larebeke, Nik</creator><creator>Willems, Jan L.</creator><creator>Schoeters, Greet</creator><general>Elsevier Ltd</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>2009</creationdate><title>The relation between the estimated dietary intake of PCDD/Fs and levels in blood in a Flemish population (50–65 years)</title><author>Bilau, Maaike ; De Henauw, Stefaan ; Schroijen, Carmen ; Bruckers, Liesbeth ; Hond, Elly Den ; Koppen, Gudrun ; Matthys, Christophe ; Van De Mieroop, Els ; Keune, Hans ; Baeyens, Willy ; Nelen, Vera ; Van Larebeke, Nik ; Willems, Jan L. ; Schoeters, Greet</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c390t-60d9e77a7e62ae5cb3371c6d64d21325de51cc8e55c2399015a8c2bde7ffb5c03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>Aged</topic><topic>Belgium</topic><topic>Biological and medical sciences</topic><topic>Biomonitoring</topic><topic>Blood Chemical Analysis</topic><topic>CALUX</topic><topic>Dioxin-like contaminants</topic><topic>Environmental pollutants toxicology</topic><topic>Female</topic><topic>FFQ</topic><topic>Flanders</topic><topic>General aspects</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Multivariate Analysis</topic><topic>Polychlorinated Dibenzodioxins - analogs & derivatives</topic><topic>Polychlorinated Dibenzodioxins - blood</topic><topic>Polychlorinated Dibenzodioxins - metabolism</topic><topic>Risk Factors</topic><topic>Surveys and Questionnaires</topic><topic>Toxicology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bilau, Maaike</creatorcontrib><creatorcontrib>De Henauw, Stefaan</creatorcontrib><creatorcontrib>Schroijen, Carmen</creatorcontrib><creatorcontrib>Bruckers, Liesbeth</creatorcontrib><creatorcontrib>Hond, Elly Den</creatorcontrib><creatorcontrib>Koppen, Gudrun</creatorcontrib><creatorcontrib>Matthys, Christophe</creatorcontrib><creatorcontrib>Van De Mieroop, Els</creatorcontrib><creatorcontrib>Keune, Hans</creatorcontrib><creatorcontrib>Baeyens, Willy</creatorcontrib><creatorcontrib>Nelen, Vera</creatorcontrib><creatorcontrib>Van Larebeke, Nik</creatorcontrib><creatorcontrib>Willems, Jan L.</creatorcontrib><creatorcontrib>Schoeters, Greet</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Environment international</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bilau, Maaike</au><au>De Henauw, Stefaan</au><au>Schroijen, Carmen</au><au>Bruckers, Liesbeth</au><au>Hond, Elly Den</au><au>Koppen, Gudrun</au><au>Matthys, Christophe</au><au>Van De Mieroop, Els</au><au>Keune, Hans</au><au>Baeyens, Willy</au><au>Nelen, Vera</au><au>Van Larebeke, Nik</au><au>Willems, Jan L.</au><au>Schoeters, Greet</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The relation between the estimated dietary intake of PCDD/Fs and levels in blood in a Flemish population (50–65 years)</atitle><jtitle>Environment international</jtitle><addtitle>Environ Int</addtitle><date>2009</date><risdate>2009</risdate><volume>35</volume><issue>1</issue><spage>9</spage><epage>13</epage><pages>9-13</pages><issn>0160-4120</issn><eissn>1873-6750</eissn><coden>ENVIDV</coden><abstract>Dioxin-like activity was measured in the serum of 1425 Flemish men and women via the CALUX assay. The adults, aged between 50 and 65 years, participated in a large biomonitoring program, executed by the Flemish Center of Expertise for Environment and Health between 2002 and 2006. Within the context of this biomonitoring program also dietary intake of dioxin-like contaminants was assessed through a food frequency questionnaire.
The relation between the estimated dietary intake and the dioxin-like activity in serum was evaluated using multivariate analyses: a logistic model was performed on the total population, while a linear regression analysis was done on the subsample with quantifiable dioxin activity levels in serum. Region, gender, age, BMI, smoking status, as well as dietary habits were entered in the model, with dioxin level as an outcome estimate.
Both the logistic and linear model confirmed the contribution of dietary intake to the dioxin activity measured in serum. Also BMI and region were found to be associated with dioxin activity levels.</abstract><cop>Oxford</cop><pub>Elsevier Ltd</pub><pmid>18602159</pmid><doi>10.1016/j.envint.2008.05.007</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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source | MEDLINE; ScienceDirect Journals (5 years ago - present) |
subjects | Aged Belgium Biological and medical sciences Biomonitoring Blood Chemical Analysis CALUX Dioxin-like contaminants Environmental pollutants toxicology Female FFQ Flanders General aspects Humans Male Medical sciences Middle Aged Multivariate Analysis Polychlorinated Dibenzodioxins - analogs & derivatives Polychlorinated Dibenzodioxins - blood Polychlorinated Dibenzodioxins - metabolism Risk Factors Surveys and Questionnaires Toxicology |
title | The relation between the estimated dietary intake of PCDD/Fs and levels in blood in a Flemish population (50–65 years) |
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