The relation between the estimated dietary intake of PCDD/Fs and levels in blood in a Flemish population (50–65 years)

Dioxin-like activity was measured in the serum of 1425 Flemish men and women via the CALUX assay. The adults, aged between 50 and 65 years, participated in a large biomonitoring program, executed by the Flemish Center of Expertise for Environment and Health between 2002 and 2006. Within the context...

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Veröffentlicht in:Environment international 2009, Vol.35 (1), p.9-13
Hauptverfasser: Bilau, Maaike, De Henauw, Stefaan, Schroijen, Carmen, Bruckers, Liesbeth, Hond, Elly Den, Koppen, Gudrun, Matthys, Christophe, Van De Mieroop, Els, Keune, Hans, Baeyens, Willy, Nelen, Vera, Van Larebeke, Nik, Willems, Jan L., Schoeters, Greet
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container_end_page 13
container_issue 1
container_start_page 9
container_title Environment international
container_volume 35
creator Bilau, Maaike
De Henauw, Stefaan
Schroijen, Carmen
Bruckers, Liesbeth
Hond, Elly Den
Koppen, Gudrun
Matthys, Christophe
Van De Mieroop, Els
Keune, Hans
Baeyens, Willy
Nelen, Vera
Van Larebeke, Nik
Willems, Jan L.
Schoeters, Greet
description Dioxin-like activity was measured in the serum of 1425 Flemish men and women via the CALUX assay. The adults, aged between 50 and 65 years, participated in a large biomonitoring program, executed by the Flemish Center of Expertise for Environment and Health between 2002 and 2006. Within the context of this biomonitoring program also dietary intake of dioxin-like contaminants was assessed through a food frequency questionnaire. The relation between the estimated dietary intake and the dioxin-like activity in serum was evaluated using multivariate analyses: a logistic model was performed on the total population, while a linear regression analysis was done on the subsample with quantifiable dioxin activity levels in serum. Region, gender, age, BMI, smoking status, as well as dietary habits were entered in the model, with dioxin level as an outcome estimate. Both the logistic and linear model confirmed the contribution of dietary intake to the dioxin activity measured in serum. Also BMI and region were found to be associated with dioxin activity levels.
doi_str_mv 10.1016/j.envint.2008.05.007
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subjects Aged
Belgium
Biological and medical sciences
Biomonitoring
Blood Chemical Analysis
CALUX
Dioxin-like contaminants
Environmental pollutants toxicology
Female
FFQ
Flanders
General aspects
Humans
Male
Medical sciences
Middle Aged
Multivariate Analysis
Polychlorinated Dibenzodioxins - analogs & derivatives
Polychlorinated Dibenzodioxins - blood
Polychlorinated Dibenzodioxins - metabolism
Risk Factors
Surveys and Questionnaires
Toxicology
title The relation between the estimated dietary intake of PCDD/Fs and levels in blood in a Flemish population (50–65 years)
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