Superparamagnetic iron oxide does not affect the viability and function of adipose-derived stem cells, and superparamagnetic iron oxide–enhanced magnetic resonance imaging identifies viable cells

Abstract The objectives of this study were (1) to determine whether superparamagnetic iron oxide (SPIO) affects viability, transdifferentiation potential and cell-factor secretion of adipose-derived stem cells (ASCs); and (2) to determine whether SPIO-enhanced magnetic resonance (MR) imaging highlig...

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Veröffentlicht in:	Magnetic resonance imaging 2009-01, Vol.27 (1), p.108-119
Hauptverfasser:	Wang, Lei, Deng, Jixian, Wang, Jian, Xiang, Bo, Yang, Tonghua, Gruwel, Marco, Kashour, Tarek, Tomanek, Boguslaw, Summer, Randy, Freed, Darren, Jassal, Davinder S, Dai, Guangping, Glogowski, Miriam, Deslauriers, Roxanne, Arora, Rakesh C, Tian, Ganghong
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipocytes - metabolism Adipocytes - physiology Adipose-derived stem cells Analysis of Variance Animals Cell Survival - physiology Cells, Cultured Contrast Media - pharmacology Dextrans Ferrosoferric Oxide Hepatocyte Growth Factor - metabolism Image Processing, Computer-Assisted Insulin-Like Growth Factor I - metabolism Iron - pharmacology Magnetic resonance imaging Magnetic Resonance Imaging - methods Magnetite Nanoparticles Male Oxides - pharmacology Radiology Rats Rats, Inbred Lew Reverse Transcriptase Polymerase Chain Reaction Staining and Labeling Stem Cells - metabolism Stem Cells - physiology Superparamagnetic iron oxide Transdifferentiation Vascular Endothelial Growth Factor A - metabolism Viability
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