Possible relationship between phenylthiocarbamide taste sensitivity and epilepsy
The study was based on the data of a sample of 400 epileptic patients (200 idiopathic and 200 symptomatic) and 100 normal healthy individuals serving as controls. The PTC threshold distribution was bimodal. The number of non-tasters among idiopathic epileptics (35.5%) and symptomatic epileptics (32....
Gespeichert in:
| Veröffentlicht in: | Neurology India 2004-06, Vol.52 (2), p.206-209 |
|---|---|
| 1. Verfasser: | |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 209 |
|---|---|
| container_issue | 2 |
| container_start_page | 206 |
| container_title | Neurology India |
| container_volume | 52 |
| creator | Pal SK, Sharma K, Pathak A, Sawhney IMS, Prabhakar S |
| description | The study was based on the data of a sample of 400 epileptic patients
(200 idiopathic and 200 symptomatic) and 100 normal healthy individuals
serving as controls. The PTC threshold distribution was bimodal. The
number of non-tasters among idiopathic epileptics (35.5%) and
symptomatic epileptics (32.5%) was significantly higher than controls
(20%). The relative incidence of non-tasters in idiopathic and
symptomatic epilepsies was 2.20 and 1.93 respectively. There is
evidence that non-tasters tend to ingest a greater quantity of bitter
tasting goitrogenic substances present naturally in edible plants which
in turn exert greater thyroid stress in non-tasters or less sensitive
tasters. Such a stress during intrauterine or early childhood growth
and development might have affected neurological maturation which in
turn made them more susceptible to epilepsy than tasters, who faced
lesser stress. |
| format | Article |
| fullrecord | <record><control><sourceid>gale_proqu</sourceid><recordid>TN_cdi_proquest_miscellaneous_66732764</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A120702753</galeid><sourcerecordid>A120702753</sourcerecordid><originalsourceid>FETCH-LOGICAL-b350t-c93c9c63a5d4362425831d55fb8a5909136e5680aa0a827fbd32cdd5d20bbff83</originalsourceid><addsrcrecordid>eNptkctq5TAMhsPQ0p5eXmEIs-guxbFix1mWMjcotIt2HWRb6XFx7Izt0-G8fQO9DAxFAiHx6ecX-lJt2mFQTcc4P6g2jHHVgFLyuDrJ-WltAVp-VB23gsuh6_mmuruLOTvtqU7ksbgY8tYttabylyjUy5bC3petiwaTxtlZqgvmQnWmkF1xz67sawy2psV5WvL-rDqc0Gc6f6un1cOP7_fXv5qb25-_r69uGg2ClcYMYAYjAYXtQPKOCwWtFWLSCsXAhhYkCakYIkPF-0lb4MZaYTnTepoUnFYXr7pLin92lMs4u2zIewwUd3mUsgfey24Fv_0HPsVdCqu3kYMcoAPFV6h5hR7R0-jCFEtC80iBEvoYaFqPG69aznrGewErf_kJv4al2ZlPF76-udjpmey4JDdj2o_vn_inqF30LtAHYZLD8X0Y3JqsYxLgBZQtloo</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>236934382</pqid></control><display><type>article</type><title>Possible relationship between phenylthiocarbamide taste sensitivity and epilepsy</title><source>MEDLINE</source><source>Bioline International Open Access</source><source>EZB-FREE-00999 freely available EZB journals</source><creator>Pal SK, Sharma K, Pathak A, Sawhney IMS, Prabhakar S</creator><creatorcontrib>Pal SK, Sharma K, Pathak A, Sawhney IMS, Prabhakar S</creatorcontrib><description>The study was based on the data of a sample of 400 epileptic patients
(200 idiopathic and 200 symptomatic) and 100 normal healthy individuals
serving as controls. The PTC threshold distribution was bimodal. The
number of non-tasters among idiopathic epileptics (35.5%) and
symptomatic epileptics (32.5%) was significantly higher than controls
(20%). The relative incidence of non-tasters in idiopathic and
symptomatic epilepsies was 2.20 and 1.93 respectively. There is
evidence that non-tasters tend to ingest a greater quantity of bitter
tasting goitrogenic substances present naturally in edible plants which
in turn exert greater thyroid stress in non-tasters or less sensitive
tasters. Such a stress during intrauterine or early childhood growth
and development might have affected neurological maturation which in
turn made them more susceptible to epilepsy than tasters, who faced
lesser stress.</description><identifier>ISSN: 0028-3886</identifier><identifier>EISSN: 1998-4022</identifier><identifier>PMID: 15269472</identifier><language>eng</language><publisher>India: Medknow Publications on behalf of the Neurological Society of India</publisher><subject>Adolescent ; Adult ; Case studies ; Case-Control Studies ; Epilepsy ; Epilepsy - physiopathology ; Female ; Humans ; Idiopathic, symptomatic, epilepsy, PTC taste sensitivity ; Male ; Phenylthiourea ; Sensory Thresholds ; Taste</subject><ispartof>Neurology India, 2004-06, Vol.52 (2), p.206-209</ispartof><rights>Copyright 2004 Neurology India.</rights><rights>COPYRIGHT 2004 Medknow Publications and Media Pvt. Ltd.</rights><rights>Copyright Medknow Publications Apr-Jun 2004</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,79426</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15269472$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Pal SK, Sharma K, Pathak A, Sawhney IMS, Prabhakar S</creatorcontrib><title>Possible relationship between phenylthiocarbamide taste sensitivity and epilepsy</title><title>Neurology India</title><addtitle>Neurol India</addtitle><description>The study was based on the data of a sample of 400 epileptic patients
(200 idiopathic and 200 symptomatic) and 100 normal healthy individuals
serving as controls. The PTC threshold distribution was bimodal. The
number of non-tasters among idiopathic epileptics (35.5%) and
symptomatic epileptics (32.5%) was significantly higher than controls
(20%). The relative incidence of non-tasters in idiopathic and
symptomatic epilepsies was 2.20 and 1.93 respectively. There is
evidence that non-tasters tend to ingest a greater quantity of bitter
tasting goitrogenic substances present naturally in edible plants which
in turn exert greater thyroid stress in non-tasters or less sensitive
tasters. Such a stress during intrauterine or early childhood growth
and development might have affected neurological maturation which in
turn made them more susceptible to epilepsy than tasters, who faced
lesser stress.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Case studies</subject><subject>Case-Control Studies</subject><subject>Epilepsy</subject><subject>Epilepsy - physiopathology</subject><subject>Female</subject><subject>Humans</subject><subject>Idiopathic, symptomatic, epilepsy, PTC taste sensitivity</subject><subject>Male</subject><subject>Phenylthiourea</subject><subject>Sensory Thresholds</subject><subject>Taste</subject><issn>0028-3886</issn><issn>1998-4022</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><sourceid>RBI</sourceid><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNptkctq5TAMhsPQ0p5eXmEIs-guxbFix1mWMjcotIt2HWRb6XFx7Izt0-G8fQO9DAxFAiHx6ecX-lJt2mFQTcc4P6g2jHHVgFLyuDrJ-WltAVp-VB23gsuh6_mmuruLOTvtqU7ksbgY8tYttabylyjUy5bC3petiwaTxtlZqgvmQnWmkF1xz67sawy2psV5WvL-rDqc0Gc6f6un1cOP7_fXv5qb25-_r69uGg2ClcYMYAYjAYXtQPKOCwWtFWLSCsXAhhYkCakYIkPF-0lb4MZaYTnTepoUnFYXr7pLin92lMs4u2zIewwUd3mUsgfey24Fv_0HPsVdCqu3kYMcoAPFV6h5hR7R0-jCFEtC80iBEvoYaFqPG69aznrGewErf_kJv4al2ZlPF76-udjpmey4JDdj2o_vn_inqF30LtAHYZLD8X0Y3JqsYxLgBZQtloo</recordid><startdate>20040601</startdate><enddate>20040601</enddate><creator>Pal SK, Sharma K, Pathak A, Sawhney IMS, Prabhakar S</creator><general>Medknow Publications on behalf of the Neurological Society of India</general><general>Medknow Publications and Media Pvt. Ltd</general><general>Medknow Publications & Media Pvt. Ltd</general><scope>RBI</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>MBDVC</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20040601</creationdate><title>Possible relationship between phenylthiocarbamide taste sensitivity and epilepsy</title><author>Pal SK, Sharma K, Pathak A, Sawhney IMS, Prabhakar S</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b350t-c93c9c63a5d4362425831d55fb8a5909136e5680aa0a827fbd32cdd5d20bbff83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2004</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Case studies</topic><topic>Case-Control Studies</topic><topic>Epilepsy</topic><topic>Epilepsy - physiopathology</topic><topic>Female</topic><topic>Humans</topic><topic>Idiopathic, symptomatic, epilepsy, PTC taste sensitivity</topic><topic>Male</topic><topic>Phenylthiourea</topic><topic>Sensory Thresholds</topic><topic>Taste</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Pal SK, Sharma K, Pathak A, Sawhney IMS, Prabhakar S</creatorcontrib><collection>Bioline International Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Research Library (Corporate)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>Neurology India</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Pal SK, Sharma K, Pathak A, Sawhney IMS, Prabhakar S</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Possible relationship between phenylthiocarbamide taste sensitivity and epilepsy</atitle><jtitle>Neurology India</jtitle><addtitle>Neurol India</addtitle><date>2004-06-01</date><risdate>2004</risdate><volume>52</volume><issue>2</issue><spage>206</spage><epage>209</epage><pages>206-209</pages><issn>0028-3886</issn><eissn>1998-4022</eissn><abstract>The study was based on the data of a sample of 400 epileptic patients
(200 idiopathic and 200 symptomatic) and 100 normal healthy individuals
serving as controls. The PTC threshold distribution was bimodal. The
number of non-tasters among idiopathic epileptics (35.5%) and
symptomatic epileptics (32.5%) was significantly higher than controls
(20%). The relative incidence of non-tasters in idiopathic and
symptomatic epilepsies was 2.20 and 1.93 respectively. There is
evidence that non-tasters tend to ingest a greater quantity of bitter
tasting goitrogenic substances present naturally in edible plants which
in turn exert greater thyroid stress in non-tasters or less sensitive
tasters. Such a stress during intrauterine or early childhood growth
and development might have affected neurological maturation which in
turn made them more susceptible to epilepsy than tasters, who faced
lesser stress.</abstract><cop>India</cop><pub>Medknow Publications on behalf of the Neurological Society of India</pub><pmid>15269472</pmid><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0028-3886 |
| ispartof | Neurology India, 2004-06, Vol.52 (2), p.206-209 |
| issn | 0028-3886 1998-4022 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_66732764 |
| source | MEDLINE; Bioline International Open Access; EZB-FREE-00999 freely available EZB journals |
| subjects | Adolescent Adult Case studies Case-Control Studies Epilepsy Epilepsy - physiopathology Female Humans Idiopathic, symptomatic, epilepsy, PTC taste sensitivity Male Phenylthiourea Sensory Thresholds Taste |
| title | Possible relationship between phenylthiocarbamide taste sensitivity and epilepsy |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-03T22%3A52%3A02IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_proqu&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Possible%20relationship%20between%20phenylthiocarbamide%20taste%20sensitivity%20and%20epilepsy&rft.jtitle=Neurology%20India&rft.au=Pal%20SK,%20Sharma%20K,%20Pathak%20A,%20Sawhney%20IMS,%20Prabhakar%20S&rft.date=2004-06-01&rft.volume=52&rft.issue=2&rft.spage=206&rft.epage=209&rft.pages=206-209&rft.issn=0028-3886&rft.eissn=1998-4022&rft_id=info:doi/&rft_dat=%3Cgale_proqu%3EA120702753%3C/gale_proqu%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=236934382&rft_id=info:pmid/15269472&rft_galeid=A120702753&rfr_iscdi=true |