Expressions of bFGF, ET-1 and SCF in dermal papilla cells and the relation to their biological properties
To investigate the expression of bFGF, ET-1 and SCF in different passages of cultured dermal papilla cells (DPC), and their possible effect on biological behaviour of DPC. The expression of bFGF, ET-1 and SCF in different passages of cultured DPC was detected by immunocytochemistry and in situ hybri...
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Veröffentlicht in: | Zhejiang da xue xue bao. Journal of Zhejiang University. Medical sciences. Yi xue ban 2004-07, Vol.33 (4), p.296-299 |
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container_title | Zhejiang da xue xue bao. Journal of Zhejiang University. Medical sciences. Yi xue ban |
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creator | Lu, Zhong-fa Wu, Jin-jin Liu, Rong-qing Zhong, Bai-yu Zheng, Min |
description | To investigate the expression of bFGF, ET-1 and SCF in different passages of cultured dermal papilla cells (DPC), and their possible effect on biological behaviour of DPC.
The expression of bFGF, ET-1 and SCF in different passages of cultured DPC was detected by immunocytochemistry and in situ hybridization.
The expression of ET-1 and SCF in early passages of cultured DPC was stronger, but became negative in late passages (>6 passages). The stronger the expression of ET-1 and SCF in DPC, the higher ability of DPC to induce hair follicle regeneration.
The expression strength of ET-1 and SCF is related to the ability of DPC inducing hair follicle regeneration. |
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The expression of bFGF, ET-1 and SCF in different passages of cultured DPC was detected by immunocytochemistry and in situ hybridization.
The expression of ET-1 and SCF in early passages of cultured DPC was stronger, but became negative in late passages (>6 passages). The stronger the expression of ET-1 and SCF in DPC, the higher ability of DPC to induce hair follicle regeneration.
The expression strength of ET-1 and SCF is related to the ability of DPC inducing hair follicle regeneration.</description><identifier>ISSN: 1008-9292</identifier><identifier>PMID: 15269978</identifier><language>chi</language><publisher>China</publisher><subject>Endothelin-1 - analysis ; Endothelin-1 - genetics ; Fibroblast Growth Factor 2 - analysis ; Fibroblast Growth Factor 2 - genetics ; Hair Follicle - chemistry ; Hair Follicle - cytology ; Hair Follicle - physiology ; Humans ; Immunohistochemistry ; In Situ Hybridization ; Stem Cell Factor - analysis ; Stem Cell Factor - genetics</subject><ispartof>Zhejiang da xue xue bao. Journal of Zhejiang University. Medical sciences. Yi xue ban, 2004-07, Vol.33 (4), p.296-299</ispartof><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15269978$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lu, Zhong-fa</creatorcontrib><creatorcontrib>Wu, Jin-jin</creatorcontrib><creatorcontrib>Liu, Rong-qing</creatorcontrib><creatorcontrib>Zhong, Bai-yu</creatorcontrib><creatorcontrib>Zheng, Min</creatorcontrib><title>Expressions of bFGF, ET-1 and SCF in dermal papilla cells and the relation to their biological properties</title><title>Zhejiang da xue xue bao. Journal of Zhejiang University. Medical sciences. Yi xue ban</title><addtitle>Zhejiang Da Xue Xue Bao Yi Xue Ban</addtitle><description>To investigate the expression of bFGF, ET-1 and SCF in different passages of cultured dermal papilla cells (DPC), and their possible effect on biological behaviour of DPC.
The expression of bFGF, ET-1 and SCF in different passages of cultured DPC was detected by immunocytochemistry and in situ hybridization.
The expression of ET-1 and SCF in early passages of cultured DPC was stronger, but became negative in late passages (>6 passages). The stronger the expression of ET-1 and SCF in DPC, the higher ability of DPC to induce hair follicle regeneration.
The expression strength of ET-1 and SCF is related to the ability of DPC inducing hair follicle regeneration.</description><subject>Endothelin-1 - analysis</subject><subject>Endothelin-1 - genetics</subject><subject>Fibroblast Growth Factor 2 - analysis</subject><subject>Fibroblast Growth Factor 2 - genetics</subject><subject>Hair Follicle - chemistry</subject><subject>Hair Follicle - cytology</subject><subject>Hair Follicle - physiology</subject><subject>Humans</subject><subject>Immunohistochemistry</subject><subject>In Situ Hybridization</subject><subject>Stem Cell Factor - analysis</subject><subject>Stem Cell Factor - genetics</subject><issn>1008-9292</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo1UEtLxDAQzkFxl3X_guTkyUIe26Q5SmlXYcGD67kk6VQDaVOTFvTf2-rKHD6G7zXMFdpSQopMMcU2aJ-SMySnXC5DbtCG5kwoJYstctXXGGHhw5Bw6LCpj_UDrs4ZxXpo8WtZYzfgFmKvPR716LzX2IL36ZefPgBH8Hpa_HgK6-4iNi748O7saolhhDg5SLfoutM-wf6CO_RWV-fyKTu9HJ_Lx1M2UsamzHRWQMsUMV1OjQCmrZUtV0TSztIC5EErEEwUhdWEaWk4YYxLIlp6ICpXfIfu_3KX6s8Z0tT0Lq0X6wHCnBohJKdCskV4dxHOpoe2GaPrdfxu_p_DfwCIw1-n</recordid><startdate>200407</startdate><enddate>200407</enddate><creator>Lu, Zhong-fa</creator><creator>Wu, Jin-jin</creator><creator>Liu, Rong-qing</creator><creator>Zhong, Bai-yu</creator><creator>Zheng, Min</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>200407</creationdate><title>Expressions of bFGF, ET-1 and SCF in dermal papilla cells and the relation to their biological properties</title><author>Lu, Zhong-fa ; Wu, Jin-jin ; Liu, Rong-qing ; Zhong, Bai-yu ; Zheng, Min</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p122t-bfc6ed290bf51b6e2acc7d39071fc18e74a9e62688ca02a7b30223706d1409593</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>chi</language><creationdate>2004</creationdate><topic>Endothelin-1 - analysis</topic><topic>Endothelin-1 - genetics</topic><topic>Fibroblast Growth Factor 2 - analysis</topic><topic>Fibroblast Growth Factor 2 - genetics</topic><topic>Hair Follicle - chemistry</topic><topic>Hair Follicle - cytology</topic><topic>Hair Follicle - physiology</topic><topic>Humans</topic><topic>Immunohistochemistry</topic><topic>In Situ Hybridization</topic><topic>Stem Cell Factor - analysis</topic><topic>Stem Cell Factor - genetics</topic><toplevel>online_resources</toplevel><creatorcontrib>Lu, Zhong-fa</creatorcontrib><creatorcontrib>Wu, Jin-jin</creatorcontrib><creatorcontrib>Liu, Rong-qing</creatorcontrib><creatorcontrib>Zhong, Bai-yu</creatorcontrib><creatorcontrib>Zheng, Min</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Zhejiang da xue xue bao. Journal of Zhejiang University. Medical sciences. Yi xue ban</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lu, Zhong-fa</au><au>Wu, Jin-jin</au><au>Liu, Rong-qing</au><au>Zhong, Bai-yu</au><au>Zheng, Min</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Expressions of bFGF, ET-1 and SCF in dermal papilla cells and the relation to their biological properties</atitle><jtitle>Zhejiang da xue xue bao. Journal of Zhejiang University. Medical sciences. Yi xue ban</jtitle><addtitle>Zhejiang Da Xue Xue Bao Yi Xue Ban</addtitle><date>2004-07</date><risdate>2004</risdate><volume>33</volume><issue>4</issue><spage>296</spage><epage>299</epage><pages>296-299</pages><issn>1008-9292</issn><abstract>To investigate the expression of bFGF, ET-1 and SCF in different passages of cultured dermal papilla cells (DPC), and their possible effect on biological behaviour of DPC.
The expression of bFGF, ET-1 and SCF in different passages of cultured DPC was detected by immunocytochemistry and in situ hybridization.
The expression of ET-1 and SCF in early passages of cultured DPC was stronger, but became negative in late passages (>6 passages). The stronger the expression of ET-1 and SCF in DPC, the higher ability of DPC to induce hair follicle regeneration.
The expression strength of ET-1 and SCF is related to the ability of DPC inducing hair follicle regeneration.</abstract><cop>China</cop><pmid>15269978</pmid><tpages>4</tpages></addata></record> |
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source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
subjects | Endothelin-1 - analysis Endothelin-1 - genetics Fibroblast Growth Factor 2 - analysis Fibroblast Growth Factor 2 - genetics Hair Follicle - chemistry Hair Follicle - cytology Hair Follicle - physiology Humans Immunohistochemistry In Situ Hybridization Stem Cell Factor - analysis Stem Cell Factor - genetics |
title | Expressions of bFGF, ET-1 and SCF in dermal papilla cells and the relation to their biological properties |
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