Interleukin-8/CXCl8 forms an autocrine loop in fetal intestinal mucosa

IL-8/CXC ligand (CXCL) 8 is ingested in high concentrations by the human fetus/neonate with amniotic fluid and human milk, and is also produced constitutively by intestinal epithelial cells (IEC). We have shown that recombinant human IL-8/CXCL8 (rhIL-8/CXCL8) protects cultured IEC against tumor necr...

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Veröffentlicht in:	Pediatric research 2004-08, Vol.56 (2), p.240-249
Hauptverfasser:	MAHESHWARI, Akhil, LACSON, Atilano, WENGE LU, FOX, Samuel E, BARLEYCORN, Aaron A, CHRISTENSEN, Robert D, CALHOUN, Darlene A
Format:	Artikel
Sprache:	eng
Schlagworte:	Autocrine Communication Biological and medical sciences Cell Death - physiology Cell Survival DNA Fragmentation Female Fetus - anatomy & histology Fetus - physiology Gastroenterology. Liver. Pancreas. Abdomen General aspects Gestational Age Humans Infant Infant, Newborn Infant, Premature Interleukin-8 - genetics Interleukin-8 - metabolism Intestinal Mucosa - cytology Intestinal Mucosa - metabolism Medical sciences Other diseases. Semiology Pregnancy Receptors, Interleukin-8A - metabolism RNA, Messenger - metabolism Stomach. Duodenum. Small intestine. Colon. Rectum. Anus Tumor Necrosis Factor-alpha - metabolism
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