Contribution of outgrowth endothelial cells from human peripheral blood on in vivo vascularization of bone tissue engineered constructs based on starch polycaprolactone scaffolds

Abstract In the present study we assessed the potential of human outgrowth endothelial cells (OEC), a subpopulation within endothelial progenitor cell cultures, to support the vascularization of a complex tissue engineered construct for bone. OEC cultured on starch polycaprolactone fiber meshes (SPC...

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Veröffentlicht in:	Biomaterials 2009-02, Vol.30 (4), p.526-534
Hauptverfasser:	Fuchs, Sabine, Ghanaati, Shahram, Orth, Carina, Barbeck, Mike, Kolbe, Marlen, Hofmann, Alexander, Eblenkamp, Markus, Gomes, Manuela, Reis, Rui L, Kirkpatrick, Charles J
Format:	Artikel
Sprache:	eng
Schlagworte:	Advanced Basic Science Animals Bone and Bones - blood supply Bone and Bones - metabolism Bone tissue engineering Cell Proliferation Coculture Techniques Collagen - metabolism Dentistry Drug Combinations Endothelial Cells - cytology Endothelial Cells - transplantation Endothelial Cells - ultrastructure Endothelial progenitor cells Gene Expression Regulation Humans Implants, Experimental In vivo test Laminin - metabolism Mice Mice, SCID Neovascularization, Physiologic Osteoblasts Osteoblasts - cytology Osteoblasts - metabolism Osteogenesis - genetics Phenotype Polyesters - metabolism Proteoglycans - metabolism Starch - metabolism Subcutaneous Tissue - metabolism Tissue Engineering Tissue Scaffolds Vascularization
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