Therapeutic time window and mechanism of tetramethylpyrazine on transient focal cerebral ischemia/reperfusion injury in rats

The purpose of this study was to explore the therapeutic time window and mechanism of tetramethylpyrazine on transient focal cerebral ischemia/reperfusion injury. Middle cerebral artery occlusion was conducted in male Sprague–Dawley rats and 20 mg/kg tetramethylpyrazine was injected intraperitoneall...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Neuroscience letters 2009-01, Vol.449 (1), p.24-27
Hauptverfasser:	Zhu, Xiao-Ling, Xiong, Li-Ze, Wang, Qiang, Liu, Zhen-Guo, Ma, Xue, Zhu, Zheng-Hua, Hu, Sheng, Gong, Gu, Chen, Shao-Yang
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis of Variance Animals Biological and medical sciences Brain Infarction - drug therapy Disease Models, Animal Focal cerebral Fundamental and applied biological sciences. Psychology Ischemia/reperfusion Ischemic Attack, Transient - drug therapy Male Medical sciences Neurologic Examination Neurology Pyrazines - therapeutic use Rats Rats, Sprague-Dawley Reperfusion Injury - drug therapy RNA, Messenger - metabolism Tetramethylpyrazine Therapeutic time window Thioredoxin Thioredoxin reductase Thioredoxins - genetics Thioredoxins - metabolism Time Factors Vascular diseases and vascular malformations of the nervous system Vasodilator Agents - therapeutic use Vertebrates: nervous system and sense organs
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!