Endocrinology of anorexia of ageing
Appetite and food intake decrease with normal ageing, predisposing to the development of under-nutrition. Under-nutrition is common in older people and has been implicated in the development and progression of chronic diseases commonly affecting the elderly, as well as in increasing mortality. An un...
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| Veröffentlicht in: | Baillière's best practice & research. Clinical endocrinology & metabolism 2004-09, Vol.18 (3), p.437-452 |
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| container_title | Baillière's best practice & research. Clinical endocrinology & metabolism |
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| creator | Chapman, Ian McPhee |
| description | Appetite and food intake decrease with normal ageing, predisposing to the development of under-nutrition. Under-nutrition is common in older people and has been implicated in the development and progression of chronic diseases commonly affecting the elderly, as well as in increasing mortality. An understanding of the factors that contribute to the physiological and pathological declines in food intake in older people is likely to aid in the development of effective forms of prevention and treatment. Ageing affects many of the endocrine factors involved in the control of appetite and feeding but few studies have been performed in humans to clarify these changes. Possible hormonal causes of the anorexia of ageing include increased activity of cholecystokinin, leptin and various cytokines and reduced activity of ghrelin and testosterone. |
| doi_str_mv | 10.1016/j.beem.2004.02.004 |
| format | Article |
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Under-nutrition is common in older people and has been implicated in the development and progression of chronic diseases commonly affecting the elderly, as well as in increasing mortality. An understanding of the factors that contribute to the physiological and pathological declines in food intake in older people is likely to aid in the development of effective forms of prevention and treatment. Ageing affects many of the endocrine factors involved in the control of appetite and feeding but few studies have been performed in humans to clarify these changes. Possible hormonal causes of the anorexia of ageing include increased activity of cholecystokinin, leptin and various cytokines and reduced activity of ghrelin and testosterone.</description><identifier>ISSN: 1521-690X</identifier><identifier>EISSN: 1878-1594</identifier><identifier>DOI: 10.1016/j.beem.2004.02.004</identifier><identifier>PMID: 15261848</identifier><language>eng</language><publisher>Netherlands: Elsevier Ltd</publisher><subject>Aged ; ageing ; Aging - physiology ; Androgens - physiology ; Animals ; Anorexia ; Appetite Regulation ; cholecystokinin ; Cholecystokinin - physiology ; cytokines ; Cytokines - physiology ; Ghrelin ; Hormones - physiology ; Humans ; leptin ; Leptin - physiology ; Neurotransmitter Agents - physiology ; Peptide Hormones - physiology ; Protein-Energy Malnutrition - epidemiology ; sarcopaenia ; testosterone</subject><ispartof>Baillière's best practice & research. 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Possible hormonal causes of the anorexia of ageing include increased activity of cholecystokinin, leptin and various cytokines and reduced activity of ghrelin and testosterone.</description><subject>Aged</subject><subject>ageing</subject><subject>Aging - physiology</subject><subject>Androgens - physiology</subject><subject>Animals</subject><subject>Anorexia</subject><subject>Appetite Regulation</subject><subject>cholecystokinin</subject><subject>Cholecystokinin - physiology</subject><subject>cytokines</subject><subject>Cytokines - physiology</subject><subject>Ghrelin</subject><subject>Hormones - physiology</subject><subject>Humans</subject><subject>leptin</subject><subject>Leptin - physiology</subject><subject>Neurotransmitter Agents - physiology</subject><subject>Peptide Hormones - physiology</subject><subject>Protein-Energy Malnutrition - epidemiology</subject><subject>sarcopaenia</subject><subject>testosterone</subject><issn>1521-690X</issn><issn>1878-1594</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE9LAzEQxYMotla_gAcpCN52nWQ32Sx4kVL_QMGLgreQJrMlZXdTk1bab29qC948vcfMmwfzI-SaQk6BivtlPkfscgZQ5sDyJCdkSGUlM8rr8jR5zmgmavgckIsYlwBFUTN6TgZpIags5ZDcTnvrTXC9b_1iN_bNWPc-4NbpX79A1y8uyVmj24hXRx2Rj6fp--Qlm709v04eZ5kpOFtn5ZxXoqkwqZQSajQlSmYEkyDSgGlukYMECxwBqWa8aQytpJUNrwurixG5O_Sugv_aYFyrzkWDbat79JuohKhYUZaQguwQNMHHGLBRq-A6HXaKgtqjUUu1R6P2aBQwlSQd3RzbN_MO7d_JkUUKPBwCmH78dhhUNA57g9YFNGtlvfuv_weZ9HMC</recordid><startdate>20040901</startdate><enddate>20040901</enddate><creator>Chapman, Ian McPhee</creator><general>Elsevier Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20040901</creationdate><title>Endocrinology of anorexia of ageing</title><author>Chapman, Ian McPhee</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c352t-4b576f7e4b588809ec4e82c628068882a5de5080d05e0e1a25ffc178d8f593da3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2004</creationdate><topic>Aged</topic><topic>ageing</topic><topic>Aging - physiology</topic><topic>Androgens - physiology</topic><topic>Animals</topic><topic>Anorexia</topic><topic>Appetite Regulation</topic><topic>cholecystokinin</topic><topic>Cholecystokinin - physiology</topic><topic>cytokines</topic><topic>Cytokines - physiology</topic><topic>Ghrelin</topic><topic>Hormones - physiology</topic><topic>Humans</topic><topic>leptin</topic><topic>Leptin - physiology</topic><topic>Neurotransmitter Agents - physiology</topic><topic>Peptide Hormones - physiology</topic><topic>Protein-Energy Malnutrition - epidemiology</topic><topic>sarcopaenia</topic><topic>testosterone</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Chapman, Ian McPhee</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Baillière's best practice & research. 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| ispartof | Baillière's best practice & research. Clinical endocrinology & metabolism, 2004-09, Vol.18 (3), p.437-452 |
| issn | 1521-690X 1878-1594 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Aged ageing Aging - physiology Androgens - physiology Animals Anorexia Appetite Regulation cholecystokinin Cholecystokinin - physiology cytokines Cytokines - physiology Ghrelin Hormones - physiology Humans leptin Leptin - physiology Neurotransmitter Agents - physiology Peptide Hormones - physiology Protein-Energy Malnutrition - epidemiology sarcopaenia testosterone |
| title | Endocrinology of anorexia of ageing |
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