Stillbirth following previous cesarean section in Bavaria/Germany 1987–2005
Background An elevated risk for unexplained stillbirth in subsequent pregnancies after cesarean section was reported in 2003. This finding would imply renewed discussions about stronger indications for cesarean sections. Objective To find out whether there is an elevated risk for stillbirth in subse...
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Veröffentlicht in: | Archives of gynecology and obstetrics 2009, Vol.279 (1), p.29-36 |
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creator | Franz, Maximilian B. Lack, Nicholas Schiessl, Barbara Mylonas, Ioannis Friese, Klaus Kainer, Franz |
description | Background
An elevated risk for unexplained stillbirth in subsequent pregnancies after cesarean section was reported in 2003. This finding would imply renewed discussions about stronger indications for cesarean sections.
Objective
To find out whether there is an elevated risk for stillbirth in subsequent pregnancies after cesarean section in our cohort in Bavaria.
Methods
As data linkage of records is not possible in Germany, we devised a suitable adjustment for bias correction. Second pregnancies in Bavaria/Germany after previous vaginal birth and previous cesarean section from 1987 to 2005 were analyzed. Risk of unexplained stillbirth was estimated by time-to-event analysis.
Results
In our cohort of 629,815 second pregnancies, no elevated stillbirth risk in pregnancies after previous cesarean section compared to previous vaginal birth was noted (crude risk 0.22% in both groups; hazard ratio (HR) 1.00;
P
= 1.0). A slightly decreased risk for stillbirth after previous cesarean section for the period of 1994–2005 (HR 0.674;
P
= 0.04) could be shown.
Conclusion
We found no elevated stillbirth risk in pregnancies after previous cesarean section. The significantly lower risk for stillbirths after previous cesarean section in the period 1994–2005 is interpreted as consequence of improved obstetric surveillance. With our adjustment for bias correction, we hope to have found a way to make our data largely comparable with other sources reported in the literature. However, because of the strict German data protection act, the Bavarian birth register is only of limited use for the presented study. |
doi_str_mv | 10.1007/s00404-008-0664-x |
format | Article |
fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_66723143</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>66723143</sourcerecordid><originalsourceid>FETCH-LOGICAL-c370t-9bc1f16b880a5e3a24800f606aa23059af6dd80a2787b36aaa7ff261e3ebecb63</originalsourceid><addsrcrecordid>eNp1kMFKAzEQhoMotlYfwIssCN7WTrK7SXrUolWoeFDPIbtNasputia7tb35Dr6hT2LKFgqCpwkz3_wZPoTOMVxjADb0ACmkMQCPgdI0Xh-gPk4TEgPD-BD1YbR9A2U9dOL9AgATzukx6mGeMshI2kdPL40py9y45j3SdVnWn8bOo6VTK1O3PiqUl05JG3lVNKa2kbHRrVxJZ-Rwolwl7SbCI85-vr4JQHaKjrQsvTrb1QF6u797HT_E0-fJ4_hmGhcJgyYe5QXWmOacg8xUIknKATQFKiVJIBtJTWezMCOMszwJXcm0JhSrROWqyGkyQFdd7tLVH63yjaiML1RZSqvC2YJSRpJgIoCXf8BF3TobbhMkBHJOcJYFCndU4WrvndJi6Uwl3UZgEFvTojMtgmmxNS3WYedil9zmlZrtN3ZqA0A6wIeRnSu3__r_1F9ga4jv</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2261882155</pqid></control><display><type>article</type><title>Stillbirth following previous cesarean section in Bavaria/Germany 1987–2005</title><source>MEDLINE</source><source>SpringerLink Journals - AutoHoldings</source><creator>Franz, Maximilian B. ; Lack, Nicholas ; Schiessl, Barbara ; Mylonas, Ioannis ; Friese, Klaus ; Kainer, Franz</creator><creatorcontrib>Franz, Maximilian B. ; Lack, Nicholas ; Schiessl, Barbara ; Mylonas, Ioannis ; Friese, Klaus ; Kainer, Franz</creatorcontrib><description>Background
An elevated risk for unexplained stillbirth in subsequent pregnancies after cesarean section was reported in 2003. This finding would imply renewed discussions about stronger indications for cesarean sections.
Objective
To find out whether there is an elevated risk for stillbirth in subsequent pregnancies after cesarean section in our cohort in Bavaria.
Methods
As data linkage of records is not possible in Germany, we devised a suitable adjustment for bias correction. Second pregnancies in Bavaria/Germany after previous vaginal birth and previous cesarean section from 1987 to 2005 were analyzed. Risk of unexplained stillbirth was estimated by time-to-event analysis.
Results
In our cohort of 629,815 second pregnancies, no elevated stillbirth risk in pregnancies after previous cesarean section compared to previous vaginal birth was noted (crude risk 0.22% in both groups; hazard ratio (HR) 1.00;
P
= 1.0). A slightly decreased risk for stillbirth after previous cesarean section for the period of 1994–2005 (HR 0.674;
P
= 0.04) could be shown.
Conclusion
We found no elevated stillbirth risk in pregnancies after previous cesarean section. The significantly lower risk for stillbirths after previous cesarean section in the period 1994–2005 is interpreted as consequence of improved obstetric surveillance. With our adjustment for bias correction, we hope to have found a way to make our data largely comparable with other sources reported in the literature. However, because of the strict German data protection act, the Bavarian birth register is only of limited use for the presented study.</description><identifier>ISSN: 0932-0067</identifier><identifier>EISSN: 1432-0711</identifier><identifier>DOI: 10.1007/s00404-008-0664-x</identifier><identifier>PMID: 18470524</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer-Verlag</publisher><subject>Adult ; Cesarean section ; Cesarean Section - adverse effects ; Cesarean Section - statistics & numerical data ; Cohort Studies ; Endocrinology ; Female ; Germany - epidemiology ; Gynecology ; Health risk assessment ; Human Genetics ; Humans ; Infant, Newborn ; Medicine ; Medicine & Public Health ; Obstetrics/Perinatology/Midwifery ; Original Article ; Pregnancy ; Proportional Hazards Models ; Stillbirth ; Stillbirth - epidemiology</subject><ispartof>Archives of gynecology and obstetrics, 2009, Vol.279 (1), p.29-36</ispartof><rights>Springer-Verlag 2008</rights><rights>Archives of Gynecology and Obstetrics is a copyright of Springer, (2008). All Rights Reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c370t-9bc1f16b880a5e3a24800f606aa23059af6dd80a2787b36aaa7ff261e3ebecb63</citedby><cites>FETCH-LOGICAL-c370t-9bc1f16b880a5e3a24800f606aa23059af6dd80a2787b36aaa7ff261e3ebecb63</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00404-008-0664-x$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00404-008-0664-x$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27923,27924,41487,42556,51318</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18470524$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Franz, Maximilian B.</creatorcontrib><creatorcontrib>Lack, Nicholas</creatorcontrib><creatorcontrib>Schiessl, Barbara</creatorcontrib><creatorcontrib>Mylonas, Ioannis</creatorcontrib><creatorcontrib>Friese, Klaus</creatorcontrib><creatorcontrib>Kainer, Franz</creatorcontrib><title>Stillbirth following previous cesarean section in Bavaria/Germany 1987–2005</title><title>Archives of gynecology and obstetrics</title><addtitle>Arch Gynecol Obstet</addtitle><addtitle>Arch Gynecol Obstet</addtitle><description>Background
An elevated risk for unexplained stillbirth in subsequent pregnancies after cesarean section was reported in 2003. This finding would imply renewed discussions about stronger indications for cesarean sections.
Objective
To find out whether there is an elevated risk for stillbirth in subsequent pregnancies after cesarean section in our cohort in Bavaria.
Methods
As data linkage of records is not possible in Germany, we devised a suitable adjustment for bias correction. Second pregnancies in Bavaria/Germany after previous vaginal birth and previous cesarean section from 1987 to 2005 were analyzed. Risk of unexplained stillbirth was estimated by time-to-event analysis.
Results
In our cohort of 629,815 second pregnancies, no elevated stillbirth risk in pregnancies after previous cesarean section compared to previous vaginal birth was noted (crude risk 0.22% in both groups; hazard ratio (HR) 1.00;
P
= 1.0). A slightly decreased risk for stillbirth after previous cesarean section for the period of 1994–2005 (HR 0.674;
P
= 0.04) could be shown.
Conclusion
We found no elevated stillbirth risk in pregnancies after previous cesarean section. The significantly lower risk for stillbirths after previous cesarean section in the period 1994–2005 is interpreted as consequence of improved obstetric surveillance. With our adjustment for bias correction, we hope to have found a way to make our data largely comparable with other sources reported in the literature. However, because of the strict German data protection act, the Bavarian birth register is only of limited use for the presented study.</description><subject>Adult</subject><subject>Cesarean section</subject><subject>Cesarean Section - adverse effects</subject><subject>Cesarean Section - statistics & numerical data</subject><subject>Cohort Studies</subject><subject>Endocrinology</subject><subject>Female</subject><subject>Germany - epidemiology</subject><subject>Gynecology</subject><subject>Health risk assessment</subject><subject>Human Genetics</subject><subject>Humans</subject><subject>Infant, Newborn</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Obstetrics/Perinatology/Midwifery</subject><subject>Original Article</subject><subject>Pregnancy</subject><subject>Proportional Hazards Models</subject><subject>Stillbirth</subject><subject>Stillbirth - epidemiology</subject><issn>0932-0067</issn><issn>1432-0711</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNp1kMFKAzEQhoMotlYfwIssCN7WTrK7SXrUolWoeFDPIbtNasputia7tb35Dr6hT2LKFgqCpwkz3_wZPoTOMVxjADb0ACmkMQCPgdI0Xh-gPk4TEgPD-BD1YbR9A2U9dOL9AgATzukx6mGeMshI2kdPL40py9y45j3SdVnWn8bOo6VTK1O3PiqUl05JG3lVNKa2kbHRrVxJZ-Rwolwl7SbCI85-vr4JQHaKjrQsvTrb1QF6u797HT_E0-fJ4_hmGhcJgyYe5QXWmOacg8xUIknKATQFKiVJIBtJTWezMCOMszwJXcm0JhSrROWqyGkyQFdd7tLVH63yjaiML1RZSqvC2YJSRpJgIoCXf8BF3TobbhMkBHJOcJYFCndU4WrvndJi6Uwl3UZgEFvTojMtgmmxNS3WYedil9zmlZrtN3ZqA0A6wIeRnSu3__r_1F9ga4jv</recordid><startdate>2009</startdate><enddate>2009</enddate><creator>Franz, Maximilian B.</creator><creator>Lack, Nicholas</creator><creator>Schiessl, Barbara</creator><creator>Mylonas, Ioannis</creator><creator>Friese, Klaus</creator><creator>Kainer, Franz</creator><general>Springer-Verlag</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>2009</creationdate><title>Stillbirth following previous cesarean section in Bavaria/Germany 1987–2005</title><author>Franz, Maximilian B. ; Lack, Nicholas ; Schiessl, Barbara ; Mylonas, Ioannis ; Friese, Klaus ; Kainer, Franz</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c370t-9bc1f16b880a5e3a24800f606aa23059af6dd80a2787b36aaa7ff261e3ebecb63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>Adult</topic><topic>Cesarean section</topic><topic>Cesarean Section - adverse effects</topic><topic>Cesarean Section - statistics & numerical data</topic><topic>Cohort Studies</topic><topic>Endocrinology</topic><topic>Female</topic><topic>Germany - epidemiology</topic><topic>Gynecology</topic><topic>Health risk assessment</topic><topic>Human Genetics</topic><topic>Humans</topic><topic>Infant, Newborn</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Obstetrics/Perinatology/Midwifery</topic><topic>Original Article</topic><topic>Pregnancy</topic><topic>Proportional Hazards Models</topic><topic>Stillbirth</topic><topic>Stillbirth - epidemiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Franz, Maximilian B.</creatorcontrib><creatorcontrib>Lack, Nicholas</creatorcontrib><creatorcontrib>Schiessl, Barbara</creatorcontrib><creatorcontrib>Mylonas, Ioannis</creatorcontrib><creatorcontrib>Friese, Klaus</creatorcontrib><creatorcontrib>Kainer, Franz</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Archives of gynecology and obstetrics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Franz, Maximilian B.</au><au>Lack, Nicholas</au><au>Schiessl, Barbara</au><au>Mylonas, Ioannis</au><au>Friese, Klaus</au><au>Kainer, Franz</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Stillbirth following previous cesarean section in Bavaria/Germany 1987–2005</atitle><jtitle>Archives of gynecology and obstetrics</jtitle><stitle>Arch Gynecol Obstet</stitle><addtitle>Arch Gynecol Obstet</addtitle><date>2009</date><risdate>2009</risdate><volume>279</volume><issue>1</issue><spage>29</spage><epage>36</epage><pages>29-36</pages><issn>0932-0067</issn><eissn>1432-0711</eissn><abstract>Background
An elevated risk for unexplained stillbirth in subsequent pregnancies after cesarean section was reported in 2003. This finding would imply renewed discussions about stronger indications for cesarean sections.
Objective
To find out whether there is an elevated risk for stillbirth in subsequent pregnancies after cesarean section in our cohort in Bavaria.
Methods
As data linkage of records is not possible in Germany, we devised a suitable adjustment for bias correction. Second pregnancies in Bavaria/Germany after previous vaginal birth and previous cesarean section from 1987 to 2005 were analyzed. Risk of unexplained stillbirth was estimated by time-to-event analysis.
Results
In our cohort of 629,815 second pregnancies, no elevated stillbirth risk in pregnancies after previous cesarean section compared to previous vaginal birth was noted (crude risk 0.22% in both groups; hazard ratio (HR) 1.00;
P
= 1.0). A slightly decreased risk for stillbirth after previous cesarean section for the period of 1994–2005 (HR 0.674;
P
= 0.04) could be shown.
Conclusion
We found no elevated stillbirth risk in pregnancies after previous cesarean section. The significantly lower risk for stillbirths after previous cesarean section in the period 1994–2005 is interpreted as consequence of improved obstetric surveillance. With our adjustment for bias correction, we hope to have found a way to make our data largely comparable with other sources reported in the literature. However, because of the strict German data protection act, the Bavarian birth register is only of limited use for the presented study.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer-Verlag</pub><pmid>18470524</pmid><doi>10.1007/s00404-008-0664-x</doi><tpages>8</tpages></addata></record> |
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source | MEDLINE; SpringerLink Journals - AutoHoldings |
subjects | Adult Cesarean section Cesarean Section - adverse effects Cesarean Section - statistics & numerical data Cohort Studies Endocrinology Female Germany - epidemiology Gynecology Health risk assessment Human Genetics Humans Infant, Newborn Medicine Medicine & Public Health Obstetrics/Perinatology/Midwifery Original Article Pregnancy Proportional Hazards Models Stillbirth Stillbirth - epidemiology |
title | Stillbirth following previous cesarean section in Bavaria/Germany 1987–2005 |
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