In vivo photoacoustic molecular imaging with simultaneous multiple selective targeting using antibody-conjugated gold nanorods

The use of gold nanorods for photoacoustic molecular imaging with simultaneous multiple targeting is reported. Multiple targeting is done by utilizing the tunable optical absorption property of gold nanorods. This technique allows multiple molecular signatures to be obtained by simply switching lase...

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Veröffentlicht in:	Optics express 2008-11, Vol.16 (23), p.18605-18615
Hauptverfasser:	Li, Pai-Chi, Wang, Churng-Ren Chris, Shieh, Dar-Bin, Wei, Chen-Wei, Liao, Chao-Kang, Poe, Carolina, Jhan, Suwen, Ding, Ann-Ann, Wu, Ya-Na
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies Computer-Aided Design Drug Delivery Systems - methods Elasticity Imaging Techniques - instrumentation Equipment Design Equipment Failure Analysis ErbB Receptors - metabolism Gold Humans Male Mice Mice, SCID Molecular Probe Techniques - instrumentation Mouth Neoplasms - diagnostic imaging Mouth Neoplasms - immunology Nanostructures - chemistry Nanostructures - ultrastructure Reproducibility of Results Sensitivity and Specificity Systems Integration
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