Tyrosinase-Inhibitory Furanocoumarin from Angelica dahurica

An extract of the roots of Angelica dahurica BENTH. et HOOK. (Umbelliferae) showed potential tyrosinase inhibition against mushroom tyrosinase. Employing a bioassay-linked HPLC method, followed by semipreparative HPLC, the active principle was isolated and characterized as 9-hydroxy-4-methoxypsorale...

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Veröffentlicht in:Biological & pharmaceutical bulletin 2004, Vol.27(7), pp.1144-1146
Hauptverfasser: Piao, Xiang Lan, Baek, Seung Hoon, Park, Man Ki, Park, Jeong Hill
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creator Piao, Xiang Lan
Baek, Seung Hoon
Park, Man Ki
Park, Jeong Hill
description An extract of the roots of Angelica dahurica BENTH. et HOOK. (Umbelliferae) showed potential tyrosinase inhibition against mushroom tyrosinase. Employing a bioassay-linked HPLC method, followed by semipreparative HPLC, the active principle was isolated and characterized as 9-hydroxy-4-methoxypsoralen.
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subjects 9-hydroxy-4-methoxypsoralen
Angelica
Angelica dahurica
Enzyme Inhibitors - chemistry
Enzyme Inhibitors - isolation & purification
Enzyme Inhibitors - pharmacology
Furocoumarins - chemistry
Furocoumarins - isolation & purification
Furocoumarins - pharmacology
LC/MS
Monophenol Monooxygenase - antagonists & inhibitors
Monophenol Monooxygenase - metabolism
Plant Extracts - chemistry
Plant Extracts - isolation & purification
Plant Extracts - pharmacology
Plant Roots
tyrosinase inhibition
title Tyrosinase-Inhibitory Furanocoumarin from Angelica dahurica
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