Osteal Complications as First Manifestation in a Patient with Primary Sjögren's Syndrome and with Associated Distal Tubular Acidosis (Type 1) and Chronic Renal Insufficiency

:  Renal affection is among the complications associated with the Sjögren's Syndrome. Tubulo‐interstitial nephritis constitutes the most frequent renal lesion and distal tubular acidosis (Type 1) is the most important clinical manifestation of this tubular dysfunction, although the occurrence o...

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Veröffentlicht in:Therapeutic apheresis and dialysis 2004-04, Vol.8 (2), p.160-163
Hauptverfasser: Díaz Rodríguez, C, González Rivero, C, Trinidad San José, JC, Del Río Romero, D, Moreno Fernández, A, Granja Romero, E
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container_end_page 163
container_issue 2
container_start_page 160
container_title Therapeutic apheresis and dialysis
container_volume 8
creator Díaz Rodríguez, C
González Rivero, C
Trinidad San José, JC
Del Río Romero, D
Moreno Fernández, A
Granja Romero, E
description :  Renal affection is among the complications associated with the Sjögren's Syndrome. Tubulo‐interstitial nephritis constitutes the most frequent renal lesion and distal tubular acidosis (Type 1) is the most important clinical manifestation of this tubular dysfunction, although the occurrence of chronic renal insufficiency is not an uncommon finding in the presence of distal renal tubular acidosis. Osteomalacia is a clinical consequence of tubular acidosis caused by buffering of H+ in the bone. We present the case of a woman with osteal complication a year before being diagnosed with primary Sjögren's Syndrome and with distal tubular acidosis and renal insufficiency associated at diagnosis.
doi_str_mv 10.1111/j.1526-0968.2003.00122.x
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Tubulo‐interstitial nephritis constitutes the most frequent renal lesion and distal tubular acidosis (Type 1) is the most important clinical manifestation of this tubular dysfunction, although the occurrence of chronic renal insufficiency is not an uncommon finding in the presence of distal renal tubular acidosis. Osteomalacia is a clinical consequence of tubular acidosis caused by buffering of H+ in the bone. 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Tubulo‐interstitial nephritis constitutes the most frequent renal lesion and distal tubular acidosis (Type 1) is the most important clinical manifestation of this tubular dysfunction, although the occurrence of chronic renal insufficiency is not an uncommon finding in the presence of distal renal tubular acidosis. Osteomalacia is a clinical consequence of tubular acidosis caused by buffering of H+ in the bone. We present the case of a woman with osteal complication a year before being diagnosed with primary Sjögren's Syndrome and with distal tubular acidosis and renal insufficiency associated at diagnosis.</abstract><cop>Melbourne, Australia</cop><pub>Blackwell Science Pty</pub><pmid>15255131</pmid><doi>10.1111/j.1526-0968.2003.00122.x</doi><tpages>4</tpages></addata></record>
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subjects Acidosis, Renal Tubular - drug therapy
Acidosis, Renal Tubular - etiology
Aged
Distal renal tubular acidosis
Female
Humans
Kidney Failure, Chronic - drug therapy
Kidney Failure, Chronic - etiology
Osteomalacia
Osteomalacia - drug therapy
Osteomalacia - etiology
Renal insufficiency
Sjogren's Syndrome - complications
Sjogren's Syndrome - diagnosis
Sjogren's Syndrome - immunology
Sjögren's Syndrome
title Osteal Complications as First Manifestation in a Patient with Primary Sjögren's Syndrome and with Associated Distal Tubular Acidosis (Type 1) and Chronic Renal Insufficiency
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