Retinal nerve fiber layer birefringence evaluated with polarization sensitive spectral domain OCT and scanning laser polarimetry: A comparison
A polarization‐sensitive spectral domain optical coherence tomography (PS‐SD‐OCT) system is used to measure phase retardation and birefringence of the human retinal nerve fiber layer (RNFL) in vivo. The instrument records three parameters simultaneously: intensity, phase retardation and optic‐axis o...
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| Veröffentlicht in: | Journal of biophotonics 2008-05, Vol.1 (2), p.129-139 |
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| creator | Götzinger, E. Pircher, M. Baumann, B. Hirn, C. Vass, C. Hitzenberger, C. K. |
| description | A polarization‐sensitive spectral domain optical coherence tomography (PS‐SD‐OCT) system is used to measure phase retardation and birefringence of the human retinal nerve fiber layer (RNFL) in vivo. The instrument records three parameters simultaneously: intensity, phase retardation and optic‐axis orientation. 3D data sets are recorded in the optic nerve‐head area of a healthy and a glaucomatous eye, and the results are presented in various ways: En‐face phase‐retardation maps of the RNFL are generated from the recorded 3D data and results are compared with scanning laser polarimetry (SLP). The depth information provided by OCT is used to segment the RNFL in the intensity image and measure the RNFL thickness. From the retardation and thickness data, 2D birefringence maps of the RNFL are derived. Circumpapillary plots of RNFL retardation and thickness obtained by PS‐SD‐OCT are quantitatively compared with those obtained by SLP. (© 2008 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim) |
| doi_str_mv | 10.1002/jbio.200710009 |
| format | Article |
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Circumpapillary plots of RNFL retardation and thickness obtained by PS‐SD‐OCT are quantitatively compared with those obtained by SLP. (© 2008 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)</description><identifier>ISSN: 1864-063X</identifier><identifier>EISSN: 1864-0648</identifier><identifier>DOI: 10.1002/jbio.200710009</identifier><identifier>PMID: 19343644</identifier><language>eng</language><publisher>Berlin: WILEY-VCH Verlag</publisher><subject>Birefringence ; Diagnostic Techniques, Ophthalmological ; Glaucoma - diagnosis ; Glaucoma - pathology ; Humans ; Lasers ; Male ; Middle Aged ; nerve fiber layer ; Nerve Fibers - pathology ; Optic Disk - pathology ; Optical coherence tomography ; polarization ; retardation ; retina ; Retinal Ganglion Cells - pathology ; scanning laser polarimetry ; Tomography, Optical Coherence</subject><ispartof>Journal of biophotonics, 2008-05, Vol.1 (2), p.129-139</ispartof><rights>Copyright © 2008 WILEY‐VCH Verlag GmbH & Co. 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K.</creatorcontrib><title>Retinal nerve fiber layer birefringence evaluated with polarization sensitive spectral domain OCT and scanning laser polarimetry: A comparison</title><title>Journal of biophotonics</title><addtitle>J. Biophoton</addtitle><description>A polarization‐sensitive spectral domain optical coherence tomography (PS‐SD‐OCT) system is used to measure phase retardation and birefringence of the human retinal nerve fiber layer (RNFL) in vivo. The instrument records three parameters simultaneously: intensity, phase retardation and optic‐axis orientation. 3D data sets are recorded in the optic nerve‐head area of a healthy and a glaucomatous eye, and the results are presented in various ways: En‐face phase‐retardation maps of the RNFL are generated from the recorded 3D data and results are compared with scanning laser polarimetry (SLP). The depth information provided by OCT is used to segment the RNFL in the intensity image and measure the RNFL thickness. From the retardation and thickness data, 2D birefringence maps of the RNFL are derived. Circumpapillary plots of RNFL retardation and thickness obtained by PS‐SD‐OCT are quantitatively compared with those obtained by SLP. (© 2008 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)</description><subject>Birefringence</subject><subject>Diagnostic Techniques, Ophthalmological</subject><subject>Glaucoma - diagnosis</subject><subject>Glaucoma - pathology</subject><subject>Humans</subject><subject>Lasers</subject><subject>Male</subject><subject>Middle Aged</subject><subject>nerve fiber layer</subject><subject>Nerve Fibers - pathology</subject><subject>Optic Disk - pathology</subject><subject>Optical coherence tomography</subject><subject>polarization</subject><subject>retardation</subject><subject>retina</subject><subject>Retinal Ganglion Cells - pathology</subject><subject>scanning laser polarimetry</subject><subject>Tomography, Optical Coherence</subject><issn>1864-063X</issn><issn>1864-0648</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkU9PFDEYhxsjEUSvHk1P3mZpp51_3nAjK4SwBDEYL02n81aLM-3QdsHlQ_iZ7WY2Kzcubd_k-T1J3x9C7yiZUULyo9vWuFlOSJUm0rxAB7QueUZKXr_cvdn3ffQ6hFtCSsIK9grt04ZxVnJ-gP5eQTRW9tiCvwesTQse93KdztZ40N7Yn2AVYLiX_UpG6PCDib_w6HrpzaOMxlkcwAYTTcqHEVT0Sde5QRqLl_NrLG2Hg5LWJlVSh6Se0gNEv_6Ij7Fyw5jm4OwbtKdlH-Dt9j5E304-X8-_ZOfLxen8-DxTnOZNRjmQPG-7RpU1k7rIZddwyRsCFdEdaAqqkDWra5LrkmnOFaUVpy3kVLeSaXaIPkze0bu7FYQoBhMU9L204FZBlGVFalaQZ0HG094J3YCzCVTehZA2J8b0Q-nXghKxqUpsqhK7qlLg_da8agfo_uPbbhLQTMCD6WH9jE6cfTpdPpVnU9aECH92Wel_i7JiVSFuLhbi8uRscfP1x6Wo2D_bgrL9</recordid><startdate>200805</startdate><enddate>200805</enddate><creator>Götzinger, E.</creator><creator>Pircher, M.</creator><creator>Baumann, B.</creator><creator>Hirn, C.</creator><creator>Vass, C.</creator><creator>Hitzenberger, C. K.</creator><general>WILEY-VCH Verlag</general><general>WILEY‐VCH Verlag</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7SP</scope><scope>7U5</scope><scope>8FD</scope><scope>L7M</scope><scope>7X8</scope></search><sort><creationdate>200805</creationdate><title>Retinal nerve fiber layer birefringence evaluated with polarization sensitive spectral domain OCT and scanning laser polarimetry: A comparison</title><author>Götzinger, E. ; Pircher, M. ; Baumann, B. ; Hirn, C. ; Vass, C. ; Hitzenberger, C. K.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4129-14e022bd9c683af52ad94a490e70fdef1ec5a838802f63f44c11741be21fba3f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Birefringence</topic><topic>Diagnostic Techniques, Ophthalmological</topic><topic>Glaucoma - diagnosis</topic><topic>Glaucoma - pathology</topic><topic>Humans</topic><topic>Lasers</topic><topic>Male</topic><topic>Middle Aged</topic><topic>nerve fiber layer</topic><topic>Nerve Fibers - pathology</topic><topic>Optic Disk - pathology</topic><topic>Optical coherence tomography</topic><topic>polarization</topic><topic>retardation</topic><topic>retina</topic><topic>Retinal Ganglion Cells - pathology</topic><topic>scanning laser polarimetry</topic><topic>Tomography, Optical Coherence</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Götzinger, E.</creatorcontrib><creatorcontrib>Pircher, M.</creatorcontrib><creatorcontrib>Baumann, B.</creatorcontrib><creatorcontrib>Hirn, C.</creatorcontrib><creatorcontrib>Vass, C.</creatorcontrib><creatorcontrib>Hitzenberger, C. 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K.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Retinal nerve fiber layer birefringence evaluated with polarization sensitive spectral domain OCT and scanning laser polarimetry: A comparison</atitle><jtitle>Journal of biophotonics</jtitle><addtitle>J. Biophoton</addtitle><date>2008-05</date><risdate>2008</risdate><volume>1</volume><issue>2</issue><spage>129</spage><epage>139</epage><pages>129-139</pages><issn>1864-063X</issn><eissn>1864-0648</eissn><abstract>A polarization‐sensitive spectral domain optical coherence tomography (PS‐SD‐OCT) system is used to measure phase retardation and birefringence of the human retinal nerve fiber layer (RNFL) in vivo. The instrument records three parameters simultaneously: intensity, phase retardation and optic‐axis orientation. 3D data sets are recorded in the optic nerve‐head area of a healthy and a glaucomatous eye, and the results are presented in various ways: En‐face phase‐retardation maps of the RNFL are generated from the recorded 3D data and results are compared with scanning laser polarimetry (SLP). The depth information provided by OCT is used to segment the RNFL in the intensity image and measure the RNFL thickness. From the retardation and thickness data, 2D birefringence maps of the RNFL are derived. Circumpapillary plots of RNFL retardation and thickness obtained by PS‐SD‐OCT are quantitatively compared with those obtained by SLP. (© 2008 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)</abstract><cop>Berlin</cop><pub>WILEY-VCH Verlag</pub><pmid>19343644</pmid><doi>10.1002/jbio.200710009</doi><tpages>11</tpages></addata></record> |
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| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Birefringence Diagnostic Techniques, Ophthalmological Glaucoma - diagnosis Glaucoma - pathology Humans Lasers Male Middle Aged nerve fiber layer Nerve Fibers - pathology Optic Disk - pathology Optical coherence tomography polarization retardation retina Retinal Ganglion Cells - pathology scanning laser polarimetry Tomography, Optical Coherence |
| title | Retinal nerve fiber layer birefringence evaluated with polarization sensitive spectral domain OCT and scanning laser polarimetry: A comparison |
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