Nuclear Export Signal Consensus Sequences Defined Using a Localization-Based Yeast Selection System

Proteins bearing nuclear export signals (NESs) are translocated to the cytoplasm from the nucleus mainly through the CRM1-dependent pathway. However, the NES consensus sequence remains poorly defined, and there are currently no high-throughput methods for identifying NESs. In this study, we report t...

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Veröffentlicht in:	Traffic (Copenhagen, Denmark) Denmark), 2008-12, Vol.9 (12), p.2053-2062
Hauptverfasser:	Kosugi, Shunichi, Hasebe, Masako, Tomita, Masaru, Yanagawa, Hiroshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Active Transport, Cell Nucleus Biological Assay - methods consensus Consensus Sequence CRM1 Databases, Protein Hydrophobic and Hydrophilic Interactions nuclear export signal Nuclear Export Signals Saccharomyces cerevisiae - genetics Saccharomyces cerevisiae - metabolism transportin
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