Extensive analysis of the 7q31 region in human prostate tumors supports TES as the best candidate tumor suppressor gene

Loss of heterozygosity (LOH) on chromosome arm 7q31 is found in many prostate tumors. Such alterations are generally associated with inactivation of tumor suppressor genes. It has been shown previously that the main region of LOH at 7q31 spans the interval between the D7S486 and D7S2460 microsatelli...

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Veröffentlicht in:	International journal of cancer 2004-09, Vol.111 (5), p.798-804
Hauptverfasser:	Chêne, Laurent, Giroud, Christiane, Desgrandchamps, François, Boccon‐Gibod, Laurent, Cussenot, Olivier, Berthon, Philippe, Latil, Alain
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Chromosomes, Human, Pair 7 - genetics Cytoskeletal Proteins Genes, Tumor Suppressor Homeodomain Proteins - analysis Homeodomain Proteins - genetics human prostate cancer Humans Immunohistochemistry LIM Domain Proteins Loss of Heterozygosity Male Medical sciences Nephrology. Urinary tract diseases Prostatic Neoplasms - genetics real‐time quantitative RT‐PCR assay Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - analysis tumor suppressor genes Tumor Suppressor Proteins - analysis Tumor Suppressor Proteins - genetics Tumors Tumors of the urinary system Urinary tract. Prostate gland
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