Assembly of an Antiparallel Homo-Adenine DNA Duplex by Small-Molecule Binding

Molecules that reversibly bind DNA and trigger the formation of non-Watson−Crick secondary structures would be useful in the design of dynamic DNA nanostructures and as potential leads for new therapeutic agents. We demonstrate that coralyne, a small crescent-shaped molecule, promotes the formation...

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Veröffentlicht in:	Journal of the American Chemical Society 2004-07, Vol.126 (28), p.8644-8645
Hauptverfasser:	Persil, Özgül, Santai, Catherine T, Jain, Swapan S, Hud, Nicholas V
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenine - chemistry Berberine Alkaloids - chemistry Binding Sites Biological and medical sciences Circular Dichroism DNA - chemistry Fundamental and applied biological sciences. Psychology Interactions. Associations Intermolecular phenomena Microscopy, Atomic Force Molecular biophysics Molecular Structure Nucleic Acid Conformation Proflavine - chemistry Temperature
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