Defective long-term repopulating ability in hematopoietic stem cells lacking the Polycomb-group gene rae28

:  The rae28 gene (rae28) is a member of a Polycomb‐group (PcG) complex 1, which is known to help maintain transcription states once these have been initiated, by generating heritable higher‐order chromatin structures. In this study, we examined the capacity of rae28‐deficient (rae28−/−) hematopoiet...

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Veröffentlicht in:European journal of haematology 2004-08, Vol.73 (2), p.75-84
Hauptverfasser: Kim, Ji Yoo, Sawada, Akihisa, Tokimasa, Sadao, Endo, Hiroko, Ozono, Keiichi, Hara, Junichi, Takihara, Yoshihiro
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Sprache:eng
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