Experimental evidence that flavonoid metal complexes may act as mimics of superoxide dismutase

Radical scavenging activities of flavonoids rutin, taxifolin, (−)-epicatechin, luteolin, and their complexes with transition metal (Fe 2+, Fe 3+, and Cu 2+) towards superoxide were determined using illumination of riboflavin as source and NBT as detector of O 2 − . The scavenger potencies of flavono...

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Veröffentlicht in:	Archives of biochemistry and biophysics 2004-08, Vol.428 (2), p.204-208
Hauptverfasser:	Kostyuk, V.A., Potapovich, A.I., Strigunova, E.N., Kostyuk, T.V., Afanas'ev, I.B.
Format:	Artikel
Sprache:	eng
Schlagworte:	(−)-Epicatechin Catechin - chemistry Copper - metabolism Dose-Response Relationship, Drug Flavonoids Flavonoids - chemistry Flavonols - chemistry Iron - metabolism Ligands Light Luteolin Metal flavonoid complexes Models, Chemical Nitroblue Tetrazolium - pharmacology Oxygen - metabolism Quercetin - analogs & derivatives Quercetin - chemistry Reactive Oxygen Species Riboflavin - chemistry Rutin Rutin - chemistry Superoxide Superoxide dismutase Superoxide Dismutase - chemistry Superoxides - metabolism Taxifolin Time Factors Ultraviolet Rays
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