Functional independence of a peptide with the sequence of human apolipoprotein A-I central region

Previous results [J. Biol. Chem. 276 (2001) 16978] indicated that an apolipoprotein A-I (apoAI) central region swings away from lipid contact in discoidal high density lipoproteins (HDL), but it is able to penetrate into the bilayer of lipid vesicles. In this work, we have studied the interaction wi...

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Veröffentlicht in:	Archives of biochemistry and biophysics 2004-08, Vol.428 (2), p.188-197
Hauptverfasser:	Toledo, Juan Domingo, Prieto, Eduardo Daniel, Gonzalez, Marina Cecilia, Soulages, José Luis, Garda, Horacio Alberto
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apolipoprotein A-I Apolipoprotein A-I - chemistry Cell Membrane - metabolism CHO Cells Cholesterol - chemistry Cholesterol - metabolism Cholesterol transfer Circular Dichroism Conformational changes Cricetinae Cross-linking Dose-Response Relationship, Drug Fluorescence Humans Light Lipid Metabolism Lipids - chemistry Lipoproteins Peptides - chemistry Protein Binding Protein Conformation Protein Structure, Tertiary Protein–lipid interaction Synthetic peptide Time Factors
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