Timing and Checkpoints in the Regulation of Mitotic Progression

Accurate chromosome segregation relies on the precise regulation of mitotic progression. Regulation involves control over the timing of mitosis and a spindle assembly checkpoint that links anaphase onset to the completion of chromosome-microtubule attachment. In this paper, we combine live-cell imag...

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Veröffentlicht in:	Developmental cell 2004-07, Vol.7 (1), p.45-60
Hauptverfasser:	Meraldi, Patrick, Draviam, Viji M, Sorger, Peter K
Format:	Artikel
Sprache:	eng
Schlagworte:	Anaphase - physiology Carrier Proteins - genetics Carrier Proteins - metabolism Cell Cycle Proteins - genetics Cytosol - metabolism Genes, cdc - physiology HeLa Cells Humans Kinetochores - metabolism Microtubules - metabolism Mitosis - genetics Nuclear Proteins - metabolism Phenotype Phosphoproteins - genetics Phosphoproteins - metabolism Protein Kinases - deficiency Protein Kinases - genetics Protein-Serine-Threonine Kinases Repressor Proteins - genetics Repressor Proteins - metabolism RNA Interference Spindle Apparatus - metabolism
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