The role of the mast cell in asthma: induction of airway hyperresponsiveness by interaction with smooth muscle?

In a recent study, the difference between asthma and eosinophilic bronchitis (a condition characterized by cough but not airway hyperresponsiveness or airflow obstruction) was infiltration of airway smooth muscle (ASM) by mast cells. Mast cells produce a variety of lipid mediators, chemokines, cytok...

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Veröffentlicht in:	Journal of allergy and clinical immunology 2004-07, Vol.114 (1), p.58-65
1. Verfasser:	Robinson, Douglas S
Format:	Artikel
Sprache:	eng
Schlagworte:	airway smooth muscle Allergies Animals Asthma Asthma - immunology Asthma - physiopathology Biological and medical sciences Biology Bronchial Hyperreactivity - immunology Cell Survival - immunology chemokines Crystal structure Cytokines Fundamental and applied biological sciences. Psychology Fundamental immunology Genotype & phenotype Histamine Humans Hypersensitivity - complications Hypersensitivity - immunology Immunoglobulin E - immunology Immunopathology Mast cells Mast Cells - immunology Mast Cells - physiology Medical sciences Mice Models, Animal Muscle, Smooth - immunology Phenotype Rodents Smooth muscle Studies
Online-Zugang:	Volltext
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